Entity Details

Primary name SP140_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13342
EntryNameSP140_HUMAN
FullNameNuclear body protein SP140
TaxID9606
Evidenceevidence at protein level
Length867
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesSP140

GO terms

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GOName
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001650 fibrillar center
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006952 defense response
GO:0016605 PML body
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000770 SAND domainDomainDomain
IPR001487 BromodomainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR004865 HSR domainDomainDomain
IPR010919 SAND-like domain superfamilyFamilyHomologous superfamily
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR030411 Nuclear body protein Sp140FamilyFamily
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR043563 Nuclear body protein Sp110/Sp140/Sp140LFamilyFamily

Diseases

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Interactions

3 interactions