Entity Details

Primary name DLG4
Entity type gene
Source Source Link

Details

PrimaryID1742
RefseqGeneNG_008391
SymbolDLG4
Namediscs large MAGUK scaffold protein 4
Chromosome17
Location17p13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-10
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsDLG4_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0002091 negative regulation of receptor internalization
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007268 chemical synaptic transmission
GO:0007399 nervous system development
GO:0007612 learning
GO:0008021 synaptic vesicle
GO:0008022 protein C-terminus binding
GO:0014069 postsynaptic density
GO:0016188 synaptic vesicle maturation
GO:0019900 kinase binding
GO:0019903 protein phosphatase binding
GO:0030054 cell junction
GO:0030165 PDZ domain binding
GO:0030666 endocytic vesicle membrane
GO:0030863 cortical cytoskeleton
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031594 neuromuscular junction
GO:0031697 beta-1 adrenergic receptor binding
GO:0031748 D1 dopamine receptor binding
GO:0031812 P2Y1 nucleotide receptor binding
GO:0032281 AMPA glutamate receptor complex
GO:0032839 dendrite cytoplasm
GO:0033130 acetylcholine receptor binding
GO:0035176 social behavior
GO:0035255 ionotropic glutamate receptor binding
GO:0035418 protein localization to synapse
GO:0035641 locomotory exploration behavior
GO:0035865 cellular response to potassium ion
GO:0043005 neuron projection
GO:0043113 receptor clustering
GO:0043197 dendritic spine
GO:0044224 juxtaparanode region of axon
GO:0044300 cerebellar mossy fiber
GO:0044306 neuron projection terminus
GO:0044309 neuron spine
GO:0044877 protein-containing complex binding
GO:0045184 establishment of protein localization
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0050806 positive regulation of synaptic transmission
GO:0050885 neuromuscular process controlling balance
GO:0060076 excitatory synapse
GO:0060997 dendritic spine morphogenesis
GO:0061098 positive regulation of protein tyrosine kinase activity
GO:0065003 protein-containing complex assembly
GO:0071625 vocalization behavior
GO:0097060 synaptic membrane
GO:0097109 neuroligin family protein binding
GO:0097110 scaffold protein binding
GO:0097113 AMPA glutamate receptor clustering
GO:0097120 receptor localization to synapse
GO:0098609 cell-cell adhesion
GO:0098839 postsynaptic density membrane
GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping
GO:0098978 glutamatergic synapse
GO:0150012 positive regulation of neuron projection arborization
GO:2000310 regulation of NMDA receptor activity
GO:2000463 positive regulation of excitatory postsynaptic potential
GO:2000821 regulation of grooming behavior

Diseases

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Interactions

165 interactions

InteractorPartnerSourcesPublicationsLink
DLG4ERBB4BioGRID, HPRD, IntAct, MINT10725395 10839362 12716924 16767099 17018285 details
DLG4KIF13BBioGRID, HPRD, IntAct10859302 details
DLG4KIF1BHPRD, IntAct12097473 details
DLG4GRIN2BBioGRID, DIP, HPRD, MINT10488080 11723117 11937501 11997254 12738960 16332682 16990796 17459877 20018661 20869595 7569905 8601796 9278515 9581762 details
DLG4GRIN2ABioGRID, DIP, HPRD, MINT10336672 10648730 11222640 11937501 12419528 14732708 16332682 16990796 17360663 17459877 18400955 20869595 21653829 22375001 23183381 7569905 8601796 9278515 9286858 details
DLG4GRIN2CBioGRID, HPRD, MINT11937501 7569905 details
DLG4GRIN1BioGRID, HPRD, MINT11506858 11937501 12068077 14732708 15030493 16767099 17459877 22375001 9009191 9502803 details
DLG4KCNA1BioGRID, HPRD, MINT11937501 12435606 7477295 8938729 details
DLG4KCNA4BioGRID, HPRD, MINT11723117 11744724 11937501 11997254 12435606 7477295 8601796 8938729 9581762 details
DLG4CRIPTBioGRID, DIP, HPRD, MINT11744724 11937501 20018661 9581762 details
DLG4NLGN1BioGRID, HPRD, MINT11937501 30864948 9278515 details
DLG4GRIN2DHPRD, MINT11937501 7569905 details
DLG4GRB2IntAct17474147 details
DLG4MED28BioGRID, MINT16964398 details
DLG4SPRR2ABioGRID, MINT18155796 details
DLG4DLGAP1BioGRID, HPRD, MINT10527873 10844022 11060025 21653829 22117215 28973854 9024696 9115257 9286858 details
DLG4SIPA1L1BioGRID, HPRD, MINT11502259 21653829 22117215 28973854 details
DLG4MDM2BioGRID, IntAct23260144 details
DLG4LRP1BioGRID, DIP, HPRD10827173 17360663 details
DLG4NET1IntAct30126976 details
DLG4CDC5LIntAct30126976 details
DLG4PKP4IntAct30126976 details
DLG4TANC1HPRD, IntAct15673434 30126976 details
DLG4RALBP1IntAct, MINT21653829 30126976 details
DLG4FRMPD4IntAct30126976 details
DLG4GUCY1A2BioGRID, HPRD, IntAct11572861 30126976 details
DLG4CYSLTR2IntAct30126976 details
DLG4CTNND2IntAct30126976 details
DLG4PRKNBioGRID, IntAct11679592 32814053 details
DLG4ACTN2BioGRID, HPRD, MINT12435606 21653829 details
DLG4DLGAP3BioGRID, MINT21653829 9115257 details
DLG4DLG4BioGRID, HPRD, MINT10995758 11937501 21653829 9182804 details
DLG4BEGAINHPRD, MINT21653829 9756850 details
DLG4DLGAP4BioGRID, HPRD, MINT21653829 9115257 details
DLG4SYNGAP1BioGRID, HPRD, MINT21653829 9581761 details
DLG4KCNJ4BioGRID, HPRD10627592 11997254 14960569 details
DLG4KCNJ2BioGRID, HPRD10627592 details
DLG4ASIC3BioGRID, HPRD15317815 details
DLG4KCNA5BioGRID, HPRD12435606 12860415 16466689 details
DLG4EXOC4BioGRID12675619 12738960 details
DLG4LRP2BioGRID, HPRD10827173 12713445 details
DLG4GRIK1BioGRID, HPRD12597860 details
DLG4GRIK2BioGRID, HPRD11276111 11279111 11744724 12597860 9808460 details
DLG4PTK2BBioGRID, HPRD12576483 details
DLG4CACNG2BioGRID, HPRD11140673 11805122 12359873 details
DLG4LRP8BioGRID, HPRD10827173 16332682 details
DLG4CASKBioGRID, HPRD12151521 details
DLG4HGSBioGRID, HPRD12151521 details
DLG4DYNLL2BioGRID10844022 details
DLG4DYNLL1BioGRID, HPRD10844022 14760703 details
DLG4SHANK2BioGRID, HPRD10527873 10844022 details
DLG4DLG3BioGRID, HPRD10026200 28973854 details
DLG4ERBB2BioGRID, HPRD10839362 details
DLG4NLGN2BioGRID, HPRD9278515 details
DLG4NLGN3BioGRID, HPRD9278515 details
DLG4GRIK5BioGRID, HPRD11279111 9808460 details
DLG4ADRB1BioGRID, HPRD10995758 11526121 16316992 details
DLG4PTPRGBioGRID, HPRD10521598 details
DLG4SEMA4CBioGRID, HPRD11134026 15978582 details
DLG4HTR2CBioGRID, HPRD12006486 details
DLG4LRRC1BioGRID, HPRD11440998 details
DLG4MAP1ABioGRID, HPRD11925566 9786987 details
DLG4NOS1BioGRID, HPRD10488080 8625413 9459447 details
DLG4FZD1BioGRID, HPRD12067714 details
DLG4FZD2BioGRID, HPRD12067714 details
DLG4FZD4BioGRID, HPRD12067714 details
DLG4FZD7BioGRID, HPRD12067714 details
DLG4KCND2BioGRID, HPRD12435606 details
DLG4KCNA2BioGRID, HPRD12435606 12438413 7477295 8938729 details
DLG4ADGRB1BioGRID, HPRD11937501 23782696 details
DLG4LIN7ABioGRID, HPRD10341223 details
DLG4CD46BioGRID, HPRD11714708 details
DLG4KHDRBS1BioGRID22745667 details
DLG4KCNA3BioGRID, HPRD12435606 17854350 21726550 8938729 details
DLG4PCDH10BioGRID23260144 details
DLG4TRAF6BioGRID28973854 details
DLG4CYLDBioGRID28973854 details
DLG4RPS6KA1BioGRID30726710 details
DLG4CRHR1BioGRID23576434 26898829 details
DLG4ARRB2BioGRID26898829 details
DLG4SLC4A7BioGRID23183381 details
DLG4DRD1BioGRID23041629 details
DLG4ADGRL1HPRD10958799 details
DLG4IL13RA1HPRD7569905 details
DLG4KCNJ10HPRD9148889 details
DLG4SEMA4FHPRD11483650 details
DLG4CNKSR2HPRD10207009 details
DLG4GDAHPRD10595517 details
DLG4CITHPRD9870942 details
DLG4GRIN3AHPRD7569905 details
DLG4NDOR1HPRD7569905 details
DLG4TAMALINHPRD12586822 details
DLG4EFNB2HPRD15458844 details
DLG4WNT3AHPRD12067714 details
DLG4GNG13HPRD16473877 details
DLG4APPMINT20573181 details
DLG4NTRK2DIP23424281 details
DLG4ARCDIP23424281 details
DLG4CLUMINT21653829 details
DLG4DLG2BioGRID, HPRD, MINT21653829 9182804 details
DLG4ADGRB2MINT21653829 details
DLG4HNRNPCMINT21653829 details
DLG4GPSM2MINT21653829 details
DLG4GOLGA2MINT21653829 details
DLG4FTH1MINT21653829 details
DLG4COX1MINT21653829 details
DLG4MPP1MINT21653829 details
DLG4LZTS2MINT21653829 details
DLG4MPNDMINT21653829 details
DLG4EEF1GMINT21653829 details
DLG4ABHD17AMINT21653829 details
DLG4WDR74MINT21653829 details
DLG4VMACMINT21653829 details
DLG4TUBB2BMINT21653829 details
DLG4TJAP1MINT21653829 details
DLG4THOC3MINT21653829 details
DLG4RASSF4MINT21653829 details
DLG4PRR16MINT21653829 details
DLG4PICK1MINT21653829 details
DLG4PEX19MINT21653829 details
DLG4PCMT1MINT21653829 details
DLG4NOMO1MINT21653829 details
DLG4KCNJ12BioGRID, HPRD14960569 15024025 details
DLG4HTR2ABioGRID, HPRD12682061 details
DLG4ADAM22BioGRID16990550 details
DLG4LGI1BioGRID16990550 details
DLG4GRIA2BioGRID16990550 details
DLG4GRIA3BioGRID16990550 details
DLG4FYNBioGRID, HPRD12419528 9892651 details
DLG4NLGN4XBioGRID, HPRD11368788 details
DLG4MAP3K10BioGRID, HPRD11152698 details
DLG4MAP3K11BioGRID11152698 details
DLG4PRKCABioGRID, HPRD11937501 details
DLG4LIN7BBioGRID, HPRD10341223 details
DLG4RAD23ABioGRID23260144 details
DLG4PTPN5BioGRID27457929 details
DLG4APPL1BioGRID27300007 details
DLG4CNTNAP2BioGRID12438413 details
DLG4BAIAP2BioGRID15255944 details
DLG4SHANK1BioGRID, HPRD10433268 15255944 details
DLG4SLC1A1BioGRID17459877 details
DLG4YES1HPRD9892651 details
DLG4LYNHPRD9892651 details
DLG4ATP2B4HPRD11274188 details
DLG4ATP2B2HPRD11274188 details
DLG4AKAP5HPRD10939335 details
DLG4ERBINHPRD11279080 details
DLG4ZDHHC17HPRD15603740 details
DLG4ARHGAP32HPRD12531901 details
DLG4HTTHPRD11319238 details
DLG4SCN5AHPRD16637659 details
DLG4MAPK12HPRD16637659 details
DLG4GLS2HPRD16637659 details
DLG4LRFN1HPRD16828986 details
DLG4SEMA4BHPRD15978582 details
DLG4SEMA4GHPRD15978582 details
DLG4SRCHPRD16990796 details
DLG4NCKIPSDHPRD16990791 details
DLG4HSPD1BioGRID, IntAct30021884 details
DLG4PRNPBioGRID, UniProt29791485 details
DLG4CUL3BioGRID21145461 details
DLG4DUSP10BioGRID28675297 details
DLG4BRPF3BioGRID31753913 details
DLG4ELAVL1BioGRID19322201 details
DLG4HNRNPH1BioGRID26760575 details