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Entity Details
Primary name
TPX2
Entity type
gene
Source
Source Link
Details
PrimaryID
22974
RefseqGene
Symbol
TPX2
Name
TPX2 microtubule nucleation factor
Chromosome
20
Location
20q11.21
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
2000-08-23
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
TPX2_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0000278
mitotic cell cycle
GO:0000922
spindle pole
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005819
spindle
GO:0005829
cytosol
GO:0005880
nuclear microtubule
GO:0006915
apoptotic process
GO:0007020
microtubule nucleation
GO:0007026
negative regulation of microtubule depolymerization
GO:0008017
microtubule binding
GO:0010389
regulation of G2/M transition of mitotic cell cycle
GO:0015630
microtubule cytoskeleton
GO:0019901
protein kinase binding
GO:0030295
protein kinase activator activity
GO:0032147
activation of protein kinase activity
GO:0043203
axon hillock
GO:0045171
intercellular bridge
GO:0051301
cell division
GO:0060236
regulation of mitotic spindle organization
GO:0061676
importin-alpha family protein binding
GO:0072686
mitotic spindle
GO:0090307
mitotic spindle assembly
GO:1901796
regulation of signal transduction by p53 class mediator
Diseases
Show/Hide Table
Interactions
105 interactions
Interactor
Partner
Sources
Publications
Link
TPX2
AURKA
BioGRID, DIP, HPRD, IntAct
12177045
14580337
14600264
18773538
19357306
20360068
22110403
26186194
26831064
28514442
details
TPX2
CRK
IntAct
17474147
details
TPX2
GRB2
IntAct
17474147
details
TPX2
NCK1
IntAct
17474147
details
TPX2
PIK3R1
BioGRID, IntAct
17474147
32203420
details
TPX2
NAP1L1
BioGRID, IntAct
21988832
details
TPX2
THAP11
BioGRID, IntAct
21988832
details
TPX2
CDK6
BioGRID, IntAct
22094256
details
TPX2
GOLGA2
BioGRID, IntAct
25416956
31515488
32296183
details
TPX2
CALR
IntAct
32814053
details
TPX2
CDH1
IntAct
32814053
details
TPX2
DLST
IntAct
32814053
details
TPX2
CDK5R1
IntAct
32814053
details
TPX2
NEK7
IntAct
32814053
details
TPX2
SIAH2
BioGRID
17716627
details
TPX2
SUMO2
BioGRID
32786267
details
TPX2
CHUK
BioGRID, DIP
17939994
details
TPX2
IKBKB
BioGRID, DIP
17939994
details
TPX2
HMMR
BioGRID, DIP, HPRD
15705883
22110403
details
TPX2
FZR1
BioGRID
16287863
details
TPX2
KPNA1
BioGRID
14600264
details
TPX2
KPNB1
BioGRID
14600264
details
TPX2
IKBKG
BioGRID
17939994
details
TPX2
AURKB
BioGRID
19357306
details
TPX2
PLEKHM1
BioGRID
27777970
details
TPX2
TPX2
HPRD
12177045
details
TPX2
CDC5L
BioGRID, MINT
20467437
details
TPX2
HDAC9
BioGRID, IntAct
23752268
details
TPX2
RBPJ
BioGRID, MINT
25609649
details
TPX2
JUN
MINT
25609649
details
TPX2
SAP130
BioGRID, IntAct
26496610
details
TPX2
AFAP1
BioGRID, IntAct
26496610
details
TPX2
MAPK14
BioGRID, IntAct
26186194
28514442
details
TPX2
RNF111
BioGRID, IntAct
28514442
details
TPX2
GSTM3
BioGRID, IntAct
26186194
28514442
details
TPX2
BRCA1
BioGRID, DIP, UniProt
22110403
25184681
29656893
details
TPX2
H3C1
BioGRID, IntAct
29568061
34079125
details
TPX2
H3C4
IntAct
29568061
details
TPX2
H3C3
IntAct
29568061
details
TPX2
H3C6
IntAct
29568061
details
TPX2
H3C11
IntAct
29568061
details
TPX2
H3C8
IntAct
29568061
details
TPX2
H3C12
IntAct
29568061
details
TPX2
H3C10
IntAct
29568061
details
TPX2
H3C2
IntAct
29568061
details
TPX2
H3C7
IntAct
29568061
details
TPX2
LMNA
BioGRID, IntAct
22412018
29568061
34079125
details
TPX2
MDC1
BioGRID, UniProt
29656893
details
TPX2
MKI67
BioGRID, IntAct
26949251
details
TPX2
H2BC5
MINT
25281560
details
TPX2
H2BC8
BioGRID, MINT
25281560
34079125
details
TPX2
H2BC7
MINT
25281560
details
TPX2
H2BC6
MINT
25281560
details
TPX2
H2BC10
MINT
25281560
details
TPX2
H2BC4
MINT
25281560
details
TPX2
ESR1
BioGRID, IntAct
31527615
details
TPX2
ARHGEF19
BioGRID, IntAct
32203420
details
TPX2
ZNF598
BioGRID
22939629
details
TPX2
NDUFA7
BioGRID
22939629
details
TPX2
THUMPD2
BioGRID
22939629
details
TPX2
DNAJC8
BioGRID
22939629
details
TPX2
MRPL53
BioGRID
22939629
details
TPX2
SERPINH1
BioGRID
22939629
details
TPX2
UBE2S
BioGRID
22939629
details
TPX2
PPIF
BioGRID
22939629
details
TPX2
SARNP
BioGRID
22939629
details
TPX2
TWF1
BioGRID
22939629
details
TPX2
SCAMP3
BioGRID
22939629
details
TPX2
RPA3
BioGRID
24332808
details
TPX2
RPA2
BioGRID
24332808
details
TPX2
RPA1
BioGRID
24332808
details
TPX2
EGLN3
BioGRID
26972000
details
TPX2
ESR2
BioGRID
29509190
details
TPX2
EZH2
BioGRID
27634302
details
TPX2
H2BC3
BioGRID
27248496
details
TPX2
ACTC1
BioGRID
30890647
details
TPX2
MACROH2A1
BioGRID
28242625
details
TPX2
PPP1CC
BioGRID
30344098
details
TPX2
HDAC2
BioGRID
30737378
details
TPX2
XRCC6
BioGRID
30585729
details
TPX2
PRDM16
BioGRID
30462309
details
TPX2
H4C1
BioGRID
30804502
details
TPX2
DYRK1A
BioGRID
30979931
details
TPX2
SQSTM1
BioGRID
30581152
details
TPX2
PLEKHA4
BioGRID
31091453
details
TPX2
NSD2
BioGRID
31248990
details
TPX2
FANCD2
BioGRID
31180492
details
TPX2
CIT
BioGRID
31586073
details
TPX2
KIF14
BioGRID
31586073
details
TPX2
KIF20A
BioGRID
31586073
details
TPX2
PRC1
BioGRID
31586073
details
TPX2
ARHGEF4
BioGRID
32203420
details
TPX2
ARHGEF9
BioGRID
32203420
details
TPX2
NGEF
BioGRID
32203420
details
TPX2
SOS2
BioGRID
32203420
details
TPX2
CIC
BioGRID
29844126
details
TPX2
BRD4
BioGRID
32416067
details
TPX2
CDC27
BioGRID
32076268
details
TPX2
CD274
BioGRID
32941674
details
TPX2
APEX1
BioGRID
34079125
details
TPX2
ASF1A
BioGRID
34079125
details
TPX2
CBX3
BioGRID
34079125
details
TPX2
RPS6
BioGRID
34079125
details
TPX2
TERF2IP
BioGRID
34079125
details
TPX2
VIRMA
BioGRID
29507755
details
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