Entity Details

Primary name ALOX5AP
Entity type gene
Source Source Link

Details

PrimaryID241
RefseqGeneNG_011963
SymbolALOX5AP
Namearachidonate 5-lipoxygenase activating protein
Chromosome13
Location13q12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAL5AP_HUMAN

GO terms

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GOName
GO:0004364 glutathione transferase activity
GO:0004464 leukotriene-C4 synthase activity
GO:0004602 glutathione peroxidase activity
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006691 leukotriene metabolic process
GO:0008047 enzyme activator activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019370 leukotriene biosynthetic process
GO:0019372 lipoxygenase pathway
GO:0031965 nuclear membrane
GO:0047485 protein N-terminus binding
GO:0050544 arachidonic acid binding
GO:0070207 protein homotrimerization
GO:0071277 cellular response to calcium ion
GO:2001301 lipoxin biosynthetic process

Diseases

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Disease IDSourceNameDescription
601367 OMIMIschemic stroke (ISCHSTR)A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Disease susceptibility is associated with variants affecting the gene represented in this entry.

Interactions

12 interactions