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Entity Details
Primary name
GRB14_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q14449
EntryName
GRB14_HUMAN
FullName
Growth factor receptor-bound protein 14
TaxID
9606
Evidence
evidence at protein level
Length
540
SequenceStatus
complete
DateCreated
1999-07-15
DateModified
2021-06-02
Ontological Relatives
Genes
GRB14
GO terms
Show/Hide Table
GO
Name
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0007165
signal transduction
GO:0008286
insulin receptor signaling pathway
GO:0010008
endosome membrane
GO:0030674
protein-macromolecule adaptor activity
GO:0030971
receptor tyrosine kinase binding
GO:0043231
intracellular membrane-bounded organelle
GO:0046627
negative regulation of insulin receptor signaling pathway
GO:0050900
leukocyte migration
Subcellular Location
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Subcellular Location
Cytoplasm
Endosome membrane
Domains
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Domain
Name
Category
Type
IPR000159
Ras-associating (RA) domain
Domain
Domain
IPR000980
SH2 domain
Domain
Domain
IPR001849
Pleckstrin homology domain
Domain
Domain
IPR011993
PH-like domain superfamily
Family
Homologous superfamily
IPR015042
BPS (Between PH and SH2) domain
Domain
Domain
IPR029071
Ubiquitin-like domain superfamily
Family
Homologous superfamily
IPR035034
Grb14, SH2 domain
Domain
Domain
IPR035035
Growth factor receptor-bound protein 14
Family
Family
IPR036860
SH2 domain superfamily
Family
Homologous superfamily
IPR039664
GRB/APBB1IP
Family
Family
IPR039665
APBB1IP, PH domain
Domain
Domain
Diseases
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Drugs
Show/Hide Table
Interactions
29 interactions
Interactor
Partner
Sources
Publications
Link
GRB14_HUMAN
INSR_HUMAN
BioGRID, DIP, HPRD, IntAct, MINT
11726652
16582879
16934761
19648926
24535599
details
GRB14_HUMAN
IGF1R_HUMAN
BioGRID, IntAct
21988832
details
GRB14_HUMAN
CDC5L_HUMAN
BioGRID, IntAct
21988832
details
GRB14_HUMAN
MET_HUMAN
BioGRID, IntAct
24728074
details
GRB14_HUMAN
STK26_HUMAN
BioGRID, IntAct
25814554
details
GRB14_HUMAN
FRS3_HUMAN
BioGRID, IntAct
25814554
details
GRB14_HUMAN
HCK_HUMAN
BioGRID, IntAct
25814554
details
GRB14_HUMAN
GOGA2_HUMAN
BioGRID, IntAct
32296183
details
GRB14_HUMAN
TRI27_HUMAN
BioGRID, IntAct
32296183
details
GRB14_HUMAN
DAPK3_HUMAN
BioGRID
12242277
details
GRB14_HUMAN
EGFR_HUMAN
BioGRID, HPRD
8647858
details
GRB14_HUMAN
PGFRB_HUMAN
BioGRID, HPRD
8647858
details
GRB14_HUMAN
TNKS2_HUMAN
BioGRID, HPRD
11278563
details
GRB14_HUMAN
FGFR1_HUMAN
BioGRID, HPRD
10713090
20932831
details
GRB14_HUMAN
CHFR_HUMAN
BioGRID
25578860
details
GRB14_HUMAN
GGYF2_HUMAN
BioGRID
16037382
details
GRB14_HUMAN
TRI55_HUMAN
BioGRID
31391242
details
GRB14_HUMAN
ERBB2_HUMAN
BioGRID
22973453
details
GRB14_HUMAN
TIE2_HUMAN
HPRD
10521483
details
GRB14_HUMAN
IRS1_HUMAN
HPRD
9748281
details
GRB14_HUMAN
NFKB1_HUMAN
IntAct
20195357
details
GRB14_HUMAN
GSK3B_HUMAN
IntAct
24535599
details
GRB14_HUMAN
RASN_HUMAN
DIP
19648926
details
GRB14_HUMAN
KPCZ_HUMAN
BioGRID, HPRD
12242277
details
GRB14_HUMAN
FTCD_HUMAN
BioGRID
11278563
details
GRB14_HUMAN
PLCG1_HUMAN
BioGRID
20932831
details
GRB14_HUMAN
PGFRA_HUMAN
HPRD
8647858
details
GRB14_HUMAN
SQSTM_HUMAN
HPRD
12242277
details
GRB14_HUMAN
M3K14_HUMAN
HPRD
12853971
details
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