Entity Details

Primary name ESPL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14674
EntryNameESPL1_HUMAN
FullNameSeparin
TaxID9606
Evidenceevidence at protein level
Length2120
SequenceStatuscomplete
DateCreated2003-03-25
DateModified2021-06-02

Ontological Relatives

GenesESPL1

GO terms

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GOName
GO:0000070 mitotic sister chromatid segregation
GO:0000212 meiotic spindle organization
GO:0000281 mitotic cytokinesis
GO:0003824 catalytic activity
GO:0004197 cysteine-type endopeptidase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0008234 cysteine-type peptidase activity
GO:0040001 establishment of mitotic spindle localization
GO:0045143 homologous chromosome segregation
GO:0045842 positive regulation of mitotic metaphase/anaphase transition
GO:0045875 negative regulation of sister chromatid cohesion
GO:0051307 meiotic chromosome separation
GO:0072686 mitotic spindle

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR005314 Peptidase C50, separaseFamilyFamily
IPR030397 SEPARIN core domainDomainDomain

Diseases

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