Entity Details

Primary name GDF2
Entity type gene
Source Source Link

Details

PrimaryID2658
RefseqGeneNG_033916
SymbolGDF2
Namegrowth differentiation factor 2
Chromosome10
Location10q11.22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-06-16
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsGDF2_HUMAN

GO terms

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GOName
GO:0001503 ossification
GO:0001525 angiogenesis
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001570 vasculogenesis
GO:0001649 osteoblast differentiation
GO:0001937 negative regulation of endothelial cell proliferation
GO:0001938 positive regulation of endothelial cell proliferation
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006879 cellular iron ion homeostasis
GO:0008083 growth factor activity
GO:0008156 negative regulation of DNA replication
GO:0010596 negative regulation of endothelial cell migration
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016525 negative regulation of angiogenesis
GO:0030308 negative regulation of cell growth
GO:0030509 BMP signaling pathway
GO:0030513 positive regulation of BMP signaling pathway
GO:0032757 positive regulation of interleukin-8 production
GO:0032924 activin receptor signaling pathway
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0045603 positive regulation of endothelial cell differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048514 blood vessel morphogenesis
GO:0051216 cartilage development
GO:0060389 pathway-restricted SMAD protein phosphorylation
GO:0060395 SMAD protein signal transduction
GO:0061036 positive regulation of cartilage development
GO:0070062 extracellular exosome
GO:0071773 cellular response to BMP stimulus
GO:2000279 negative regulation of DNA biosynthetic process

Diseases

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Interactions

6 interactions