Entity Details

Primary name LPIN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14693
EntryNameLPIN1_HUMAN
FullNamePhosphatidate phosphatase LPIN1
TaxID9606
Evidenceevidence at protein level
Length890
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesLPIN1

GO terms

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GOName
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006642 triglyceride mobilization
GO:0006646 phosphatidylethanolamine biosynthetic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0006656 phosphatidylcholine biosynthetic process
GO:0007077 mitotic nuclear membrane disassembly
GO:0008195 phosphatidate phosphatase activity
GO:0009062 fatty acid catabolic process
GO:0019432 triglyceride biosynthetic process
GO:0031100 animal organ regeneration
GO:0031642 negative regulation of myelination
GO:0031965 nuclear membrane
GO:0032869 cellular response to insulin stimulus
GO:0044255 cellular lipid metabolic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046473 phosphatidic acid metabolic process
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1903730 regulation of phosphatidate phosphatase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Nucleus membrane

Domains

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DomainNameCategoryType
IPR007651 Lipin, N-terminalDomainDomain
IPR013209 Lipin/Ned1/Smp2 (LNS2)DomainDomain
IPR026058 LIPIN familyFamilyFamily
IPR028794 Phosphatidate phosphatase LPIN1FamilyFamily
IPR031315 LNS2/PITPDomainDomain
IPR031703 Lipin, middle domainDomainDomain
IPR036412 HAD-like superfamilyFamilyHomologous superfamily

Diseases

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