Entity Details

Primary name ABL2
Entity type gene
Source Source Link

Details

PrimaryID27
RefseqGeneNG_028242
SymbolABL2
NameABL proto-oncogene 2, non-receptor tyrosine kinase
Chromosome1
Location1q25.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-11
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsABL2_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001784 phosphotyrosine residue binding
GO:0003785 actin monomer binding
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006464 cellular protein modification process
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0010506 regulation of autophagy
GO:0010863 positive regulation of phospholipase C activity
GO:0010976 positive regulation of neuron projection development
GO:0015629 actin cytoskeleton
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019221 cytokine-mediated signaling pathway
GO:0030100 regulation of endocytosis
GO:0030145 manganese ion binding
GO:0030155 regulation of cell adhesion
GO:0035024 negative regulation of Rho protein signal transduction
GO:0035640 exploration behavior
GO:0051015 actin filament binding
GO:0051353 positive regulation of oxidoreductase activity
GO:0071300 cellular response to retinoic acid
GO:2000145 regulation of cell motility
GO:2000249 regulation of actin cytoskeleton reorganization

Diseases

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Interactions

71 interactions

InteractorPartnerSourcesPublicationsLink
ABL2ERBB3BioGRID, MINT16273093 22973453 details
ABL2ERBB4BioGRID, MINT16273093 22973453 details
ABL2ERBB2BioGRID, MINT16273093 19275932 22973453 details
ABL2EGFRBioGRID, IntAct, MINT16273093 24658140 25402006 31980649 details
ABL2CRKBioGRID, HPRD, IntAct11956190 12198159 15886098 17474147 19380743 25814554 8194526 8875975 9480911 9642287 details
ABL2PLCG1IntAct17474147 details
ABL2SRCIntAct17474147 details
ABL2FYNIntAct17474147 details
ABL2GRB2BioGRID, IntAct17474147 8194526 details
ABL2NCK1BioGRID, IntAct17474147 25241761 details
ABL2PIK3R1IntAct17474147 details
ABL2MED28BioGRID, MINT16964398 details
ABL2ABI1MINT20598684 details
ABL2MAP3K10BioGRID, IntAct20936779 details
ABL2HCKBioGRID, HPRD, IntAct12748290 21988832 details
ABL2TPD52L1BioGRID, IntAct21988832 details
ABL2FBXO38BioGRID, IntAct21988832 details
ABL2C15orf48BioGRID, IntAct21988832 details
ABL2OIP5BioGRID, IntAct21988832 details
ABL2ARBioGRID, IntAct24728074 details
ABL2KITBioGRID, IntAct24728074 details
ABL2METBioGRID, IntAct24728074 details
ABL2PIK3R3BioGRID, IntAct25814554 details
ABL2STAT3BioGRID, IntAct25814554 details
ABL2LRRK2IntAct24947832 details
ABL2TRIP10BioGRID, DIP, IntAct18330356 32296183 details
ABL2ABI2BioGRID, IntAct28514442 32296183 details
ABL2CAV1DIP20808760 details
ABL2FLT3MINT28086240 details
ABL2ABL1BioGRID, HPRD12569093 15735735 details
ABL2CATBioGRID, HPRD12777400 details
ABL2SORBS2BioGRID, HPRD9211900 details
ABL2EPHB2BioGRID, HPRD11494128 details
ABL2NEDD4BioGRID19953087 details
ABL2NEDD4LBioGRID19953087 details
ABL2PSMA7BioGRID16678104 details
ABL2DOK1BioGRID22974441 details
ABL2GPX1BioGRID, HPRD12893824 details
ABL2ABL2BioGRID15735735 15886098 details
ABL2MDM2BioGRID25624478 details
ABL2PDGFRBBioGRID19275932 details
ABL2ZMAT1BioGRID32296183 details
ABL2PRRG4BioGRID23873930 details
ABL2RIN1BioGRID, HPRD, IntAct15886098 28514442 details
ABL2CTTNmbinfo21257711 details
ABL2SF1IntAct26420826 details
ABL2EPHA4IntAct31413325 details
ABL2JAK1BioGRID9774693 details
ABL2AXLBioGRID18346204 details
ABL2BCRHPRD1383690 details
ABL2SIVA1HPRD11278261 details
ABL2HRASBioGRID, IntAct15886098 details
ABL2MPIG6BIntAct23322602 details
ABL2PTPN18IntAct23322602 details
ABL2PECAM1IntAct23322602 details
ABL2CASS4IntAct23322602 details
ABL2CD84IntAct23322602 details
ABL2CDC37BioGRID, IntAct25036637 details
ABL2PKMIntAct24606918 details
ABL2NCK2BioGRID, IntAct26186194 28514442 details
ABL2HSPBP1BioGRID, IntAct28514442 details
ABL2HSPA8BioGRID, IntAct28514442 29568061 details
ABL2BAG5BioGRID, IntAct26186194 28514442 details
ABL2NTRK1BioGRID25921289 details
ABL2BICD1BioGRID28718761 details
ABL2BICD2BioGRID28718761 details
ABL2CUL4ABioGRID30945288 details
ABL2KRASBioGRID34079125 details
ABL2VIMBioGRID34079125 details
ABL2TRIM25BioGRID29117863 details
ABL2VIRMABioGRID29507755 details