Entity Details

Primary name KCAB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14722
EntryNameKCAB1_HUMAN
FullNameVoltage-gated potassium channel subunit beta-1
TaxID9606
Evidenceevidence at protein level
Length419
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesKCNAB1

GO terms

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GOName
GO:0004033 aldo-keto reductase (NADP) activity
GO:0005249 voltage-gated potassium channel activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006813 potassium ion transport
GO:0007420 brain development
GO:0007507 heart development
GO:0007519 skeletal muscle tissue development
GO:0008076 voltage-gated potassium channel complex
GO:0015459 potassium channel regulator activity
GO:0019904 protein domain specific binding
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0032839 dendrite cytoplasm
GO:0034705 potassium channel complex
GO:0043204 perikaryon
GO:0044224 juxtaparanode region of axon
GO:0044325 transmembrane transporter binding
GO:0045445 myoblast differentiation
GO:0047834 D-threo-aldose 1-dehydrogenase activity
GO:0060539 diaphragm development
GO:0070402 NADPH binding
GO:0071805 potassium ion transmembrane transport
GO:1901379 regulation of potassium ion transmembrane transport
GO:1902259 regulation of delayed rectifier potassium channel activity
GO:1902260 negative regulation of delayed rectifier potassium channel activity
GO:1903817 negative regulation of voltage-gated potassium channel activity
GO:1990635 proximal dendrite

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-relatedFamilyFamily
IPR005400 Potassium channel, voltage-dependent, beta subunit, KCNAB1FamilyFamily
IPR005983 Potassium channel, voltage-dependent, beta subunit, KCNABFamilyFamily
IPR023210 NADP-dependent oxidoreductase domainDomainDomain
IPR036812 NADP-dependent oxidoreductase domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule