Entity Details

Primary name SETD2
Entity type gene
Source Source Link

Details

PrimaryID29072
RefseqGeneNG_032091
SymbolSETD2
NameSET domain containing 2, histone lysine methyltransferase
Chromosome3
Location3p21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-08
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsSETD2_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001763 morphogenesis of a branching structure
GO:0001843 neural tube closure
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0006298 mismatch repair
GO:0006355 regulation of transcription, DNA-templated
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0010569 regulation of double-strand break repair via homologous recombination
GO:0010793 regulation of mRNA export from nucleus
GO:0016032 viral process
GO:0016279 protein-lysine N-methyltransferase activity
GO:0018023 peptidyl-lysine trimethylation
GO:0018024 histone-lysine N-methyltransferase activity
GO:0018026 peptidyl-lysine monomethylation
GO:0030900 forebrain development
GO:0032465 regulation of cytokinesis
GO:0032727 positive regulation of interferon-alpha production
GO:0034340 response to type I interferon
GO:0034728 nucleosome organization
GO:0035441 cell migration involved in vasculogenesis
GO:0035987 endodermal cell differentiation
GO:0043014 alpha-tubulin binding
GO:0046872 metal ion binding
GO:0046975 histone methyltransferase activity (H3-K36 specific)
GO:0048332 mesoderm morphogenesis
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048863 stem cell differentiation
GO:0048864 stem cell development
GO:0051607 defense response to virus
GO:0060039 pericardium development
GO:0060669 embryonic placenta morphogenesis
GO:0060977 coronary vasculature morphogenesis
GO:0097198 histone H3-K36 trimethylation
GO:0097676 histone H3-K36 dimethylation
GO:1902850 microtubule cytoskeleton organization involved in mitosis
GO:1905634 regulation of protein localization to chromatin

Diseases

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Interactions

64 interactions

InteractorPartnerSourcesPublicationsLink
SETD2ATXN1BioGRID, HPRD, IntAct16713569 details
SETD2CICBioGRID, HPRD, IntAct16713569 details
SETD2SMAD3BioGRID, IntAct21988832 details
SETD2SIAH2BioGRID, IntAct21988832 details
SETD2HTTBioGRID, HPRD, IntAct17500595 24412394 9700202 details
SETD2H3C1BioGRID16118227 27528607 details
SETD2SETD2BioGRID, HPRD16118227 9700202 details
SETD2POLR2ABioGRID16118227 24462114 details
SETD2H3-4BioGRID24412544 details
SETD2SPOPBioGRID28805822 31911863 details
SETD2ARXMINT21653829 details
SETD2IWS1BioGRID19141475 24462114 details
SETD2TP53BioGRID18585004 details
SETD2GANBioGRID26460568 details
SETD2PCGF1BioGRID27505670 details
SETD2FGFR2BioGRID24462114 details
SETD2RPA1BioGRID24931610 details
SETD2RAD51BioGRID24931610 details
SETD2RNGTTBioGRID29395067 details
SETD2CBX8BioGRID, UniProt21282530 details
SETD2CLK2BioGRID, IntAct23602568 28514442 details
SETD2RASSF8BioGRID, IntAct26496610 details
SETD2NXF2BioGRID, IntAct28514442 details
SETD2NXF2BIntAct28514442 details
SETD2HSPB8BioGRID, IntAct28514442 details
SETD2TRPC4APBioGRID, IntAct28514442 details
SETD2F9BioGRID, IntAct28514442 details
SETD2WDR37BioGRID, IntAct26186194 28514442 details
SETD2HNRNPLLBioGRID, IntAct28514442 details
SETD2PIP4K2ABioGRID, IntAct28514442 details
SETD2AURKABioGRID, IntAct26186194 28514442 details
SETD2CPNE7BioGRID, IntAct28514442 details
SETD2JMJD6BioGRID, IntAct28514442 details
SETD2RSBN1BioGRID, IntAct28514442 details
SETD2SCARA3BioGRID, IntAct26186194 28514442 details
SETD2MDC1BioGRID, UniProt29656893 details
SETD2NPM1BioGRID, IntAct30021884 details
SETD2CENPFBioGRID, IntAct30021884 details
SETD2ESR1BioGRID, IntAct31527615 details
SETD2SOX2BioGRID, MINT23667531 details
SETD2ARHGEF10BioGRID26186194 28514442 details
SETD2LUC7LBioGRID26186194 details
SETD2EIF3IBioGRID26344197 details
SETD2XPO1BioGRID26673895 details
SETD2ESR2BioGRID29509190 details
SETD2H4C1BioGRID30804502 details
SETD2DCAF4BioGRID30945288 details
SETD2CUL7BioGRID31343991 details
SETD2MYCNBioGRID31856871 details
SETD2AURKBBioGRID31586073 details
SETD2BRPF3BioGRID31753913 details
SETD2CECR2BioGRID31753913 details
SETD2SP110BioGRID31753913 details
SETD2TRIM66BioGRID31753913 details
SETD2BRD4BioGRID32416067 details
SETD2APEX1BioGRID34079125 details
SETD2DDX23BioGRID34079125 details
SETD2DHX40BioGRID34079125 details
SETD2DHX8BioGRID34079125 details
SETD2TERF2IPBioGRID34079125 details
SETD2ELAVL1BioGRID19322201 details
SETD2TRIM25BioGRID29117863 details
SETD2VIRMABioGRID29507755 details
SETD2DDX58BioGRID32513696 details