Entity Details

Primary name HLA-G
Entity type gene
Source Source Link

Details

PrimaryID3135
RefseqGeneNG_029039
SymbolHLA-G
Namemajor histocompatibility complex, class I, G
Chromosome6
Location6p22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-10-04
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsHLAG_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001915 negative regulation of T cell mediated cytotoxicity
GO:0002451 peripheral B cell tolerance induction
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002645 positive regulation of tolerance induction
GO:0002666 positive regulation of T cell tolerance induction
GO:0002729 positive regulation of natural killer cell cytokine production
GO:0002767 immune response-inhibiting cell surface receptor signaling pathway
GO:0005102 signaling receptor binding
GO:0005615 extracellular space
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0006968 cellular defense response
GO:0009897 external side of plasma membrane
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016020 membrane
GO:0016525 negative regulation of angiogenesis
GO:0030670 phagocytic vesicle membrane
GO:0031527 filopodium membrane
GO:0031901 early endosome membrane
GO:0032735 positive regulation of interleukin-12 production
GO:0033106 cis-Golgi network membrane
GO:0042130 negative regulation of T cell proliferation
GO:0042270 protection from natural killer cell mediated cytotoxicity
GO:0042605 peptide antigen binding
GO:0042610 CD8 receptor binding
GO:0042612 MHC class I protein complex
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0045591 positive regulation of regulatory T cell differentiation
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity
GO:0050776 regulation of immune response
GO:0050777 negative regulation of immune response
GO:0051898 negative regulation of protein kinase B signaling
GO:0055038 recycling endosome membrane
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0060907 positive regulation of macrophage cytokine production
GO:0070207 protein homotrimerization
GO:0070317 negative regulation of G0 to G1 transition
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
GO:2000353 positive regulation of endothelial cell apoptotic process
GO:2000774 positive regulation of cellular senescence
GO:2001199 negative regulation of dendritic cell differentiation

Diseases

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