Entity Details

Primary name HTR2C
Entity type gene
Source Source Link

Details

PrimaryID3358
RefseqGeneNG_012082
SymbolHTR2C
Name5-hydroxytryptamine receptor 2C
ChromosomeX
LocationXq23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-07-06
ModificationDate2021-06-11

Ontological Relatives

UniProt IDs5HT2C_HUMAN

GO terms

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GOName
GO:0001587 Gq/11-coupled serotonin receptor activity
GO:0001662 behavioral fear response
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007208 phospholipase C-activating serotonin receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007626 locomotory behavior
GO:0007631 feeding behavior
GO:0010513 positive regulation of phosphatidylinositol biosynthetic process
GO:0019934 cGMP-mediated signaling
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0031644 regulation of nervous system process
GO:0032098 regulation of appetite
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0043397 regulation of corticotropin-releasing hormone secretion
GO:0045202 synapse
GO:0045600 positive regulation of fat cell differentiation
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051378 serotonin binding
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
GO:0098664 G protein-coupled serotonin receptor signaling pathway
GO:0098666 G protein-coupled serotonin receptor complex

Diseases

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Interactions

127 interactions

InteractorPartnerSourcesPublicationsLink
HTR2CMPDZBioGRID, HPRD, MINT11150294 12682077 9537516 details
HTR2CSLC39A9BioGRID, IntAct32296183 details
HTR2CEMP1BioGRID, IntAct32296183 details
HTR2CTMEM147BioGRID, IntAct28514442 32296183 details
HTR2CTMBIM6BioGRID, IntAct32296183 details
HTR2CCNIH1BioGRID, IntAct32296183 details
HTR2CSLC39A1BioGRID, IntAct, MINT28298427 28514442 details
HTR2CRTN4BioGRID, IntAct, MINT28298427 28514442 details
HTR2CATP2B3BioGRID, MINT28298427 details
HTR2CGJA1BioGRID, MINT28298427 details
HTR2CSGCBBioGRID, MINT28298427 details
HTR2CCRELD1BioGRID, MINT28298427 details
HTR2CGHITMBioGRID, MINT28298427 details
HTR2CATP6V0CBioGRID, MINT28298427 details
HTR2CC4orf3BioGRID, MINT28298427 details
HTR2CMFSD14ABioGRID, MINT28298427 details
HTR2CERG28BioGRID, MINT28298427 details
HTR2CTMEM94BioGRID, MINT28298427 details
HTR2CATP6AP2BioGRID, MINT28298427 details
HTR2CGPR37BioGRID, MINT28298427 details
HTR2CSLC29A1BioGRID, MINT28298427 details
HTR2CGPRC5BBioGRID, MINT28298427 details
HTR2CPLP1BioGRID, MINT28298427 details
HTR2CTM9SF2BioGRID, MINT28298427 details
HTR2CSPNS1BioGRID, MINT28298427 details
HTR2CTPI1BioGRID, MINT28298427 details
HTR2CCBX3BioGRID, MINT28298427 details
HTR2CLIN7CBioGRID, HPRD, MINT12006486 28298427 details
HTR2CSCRIBIntAct30126976 details
HTR2CDLG1IntAct30126976 details
HTR2CHTR2AIntAct28258217 30157263 details
HTR2CADRB2IntAct15518545 30157263 details
HTR2CHTR2CHPRD, IntAct15518545 16195233 25770211 28258217 details
HTR2CHTR2BIntAct28258217 details
HTR2CMTNR1AIntAct25770211 details
HTR2CMTNR1BIntAct25770211 details
HTR2CCHRM4IntAct15518545 details
HTR2CGHSRIntAct25727097 details
HTR2CDLG4BioGRID, HPRD12006486 details
HTR2CAPBA1BioGRID, HPRD12006486 details
HTR2CCALM1BioGRID, HPRD18768750 details
HTR2CSNTA1BioGRID15123239 details
HTR2CGNAQHPRD11916537 details
HTR2CARRB2HPRD18768750 details
HTR2CPPM1GBioGRID, IntAct28330616 details
HTR2CKNTC1BioGRID, IntAct28514442 details
HTR2CMRS2BioGRID, IntAct28514442 details
HTR2CGPR50BioGRID, IntAct28514442 details
HTR2CTNPO3BioGRID, IntAct28514442 details
HTR2CPTRH2BioGRID, IntAct28514442 details
HTR2CANGEL1BioGRID, IntAct28514442 details
HTR2CXPO7BioGRID, IntAct28514442 details
HTR2CIPO11BioGRID, IntAct28514442 details
HTR2CSEC63BioGRID, IntAct28514442 details
HTR2CC19orf25BioGRID, IntAct28514442 details
HTR2CRMND1BioGRID, IntAct28514442 details
HTR2CPDS5BBioGRID, IntAct28514442 details
HTR2CSERINC1BioGRID, IntAct28514442 details
HTR2CEIF2B3BioGRID, IntAct28514442 details
HTR2CGPRC5CBioGRID, IntAct28514442 details
HTR2CTM9SF3BioGRID, IntAct28514442 details
HTR2CNT5C3ABioGRID, IntAct28514442 details
HTR2CITPABioGRID, IntAct28514442 details
HTR2CALG8BioGRID, IntAct28514442 details
HTR2CNCAPGBioGRID, IntAct28514442 details
HTR2CIPO9BioGRID, IntAct28514442 details
HTR2CMBOAT7BioGRID, IntAct28514442 details
HTR2CFAM210BBioGRID, IntAct28514442 details
HTR2CCERS2BioGRID, IntAct28514442 details
HTR2CTVP23C-CDRT4IntAct28514442 details
HTR2CTVP23CBioGRID, IntAct28514442 details
HTR2CFAM241BBioGRID, IntAct28514442 details
HTR2CGLMNBioGRID, IntAct28514442 details
HTR2CSFXN5BioGRID, IntAct28514442 details
HTR2CCIP2ABioGRID, IntAct28514442 details
HTR2CTBC1D15BioGRID, IntAct28514442 details
HTR2CSLC35G2BioGRID, IntAct28514442 details
HTR2CGOLGA5BioGRID, IntAct28514442 details
HTR2CRETREG2BioGRID, IntAct28514442 details
HTR2CARL10BioGRID, IntAct28514442 details
HTR2CFITM2BioGRID, IntAct28514442 details
HTR2CCERS5BioGRID, IntAct28514442 details
HTR2CSLC35F2BioGRID, IntAct28514442 details
HTR2CLRRC8ABioGRID, IntAct28514442 details
HTR2CRETREG3BioGRID, IntAct28514442 details
HTR2CCAND1BioGRID, IntAct28514442 details
HTR2CUBE2Q1BioGRID, IntAct28514442 details
HTR2CHEATR3BioGRID, IntAct28514442 details
HTR2CDPY19L4BioGRID, IntAct28514442 details
HTR2CTMPPEBioGRID, IntAct28514442 details
HTR2CCERS6BioGRID, IntAct28514442 details
HTR2CPDXDC1BioGRID, IntAct28514442 details
HTR2CLPCAT3BioGRID, IntAct28514442 details
HTR2CRINT1BioGRID, IntAct28514442 details
HTR2CITPRIPL1BioGRID, IntAct28514442 details
HTR2CLMBRD2BioGRID, IntAct28514442 details
HTR2CSLC35F1BioGRID, IntAct28514442 details
HTR2CALG10BioGRID, IntAct28514442 details
HTR2CNCAPD2BioGRID, IntAct28514442 details
HTR2CEFR3ABioGRID, IntAct28514442 details
HTR2CMTX1BioGRID, IntAct28514442 details
HTR2CASPHBioGRID, IntAct28514442 details
HTR2CCAV1BioGRID, IntAct28514442 details
HTR2CATP2B2BioGRID, IntAct28514442 details
HTR2CGNB2BioGRID, IntAct28514442 details
HTR2CACTA2BioGRID, IntAct28514442 details
HTR2CHMOX2BioGRID, IntAct28514442 details
HTR2CATP5PBBioGRID, IntAct28514442 details
HTR2CLGALS3BioGRID, IntAct28514442 details
HTR2CACP2BioGRID, IntAct28514442 details
HTR2CATP5F1BBioGRID, IntAct28514442 details
HTR2CATP8BioGRID, IntAct28514442 details
HTR2CC6orf47BioGRID, IntAct28514442 details
HTR2CIPO7BioGRID, IntAct28514442 details
HTR2CCAND2BioGRID, IntAct28514442 details
HTR2CSLC19A2BioGRID, IntAct28514442 details
HTR2CFADS1BioGRID, IntAct28514442 details
HTR2CEXTL3BioGRID, IntAct28514442 details
HTR2CSYNGR2BioGRID, IntAct28514442 details
HTR2CTAPBPBioGRID, IntAct28514442 details
HTR2CBTAF1BioGRID, IntAct28514442 details
HTR2CGPR89BIntAct28514442 details
HTR2CGPR89ABioGRID, IntAct28514442 details
HTR2CRBM14-RBM4BioGRID, IntAct28514442 details
HTR2CRBM14IntAct28514442 details
HTR2CKLRG2BioGRID, IntAct28514442 details
HTR2CTNPO2BioGRID28514442 details