Entity Details

Primary name PDIA6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15084
EntryNamePDIA6_HUMAN
FullNameProtein disulfide-isomerase A6
TaxID9606
Evidenceevidence at protein level
Length440
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPDIA6

GO terms

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GOName
GO:0003756 protein disulfide isomerase activity
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006457 protein folding
GO:0034663 endoplasmic reticulum chaperone complex
GO:0036498 IRE1-mediated unfolded protein response
GO:0042470 melanosome
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum lumen
Melanosome

Domains

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DomainNameCategoryType
IPR005788 Disulphide isomeraseDomainDomain
IPR013766 Thioredoxin domainDomainDomain
IPR017937 Thioredoxin, conserved siteSiteConserved site
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily
IPR044569 Protein disulfide-isomerase A6-likeFamilyFamily

Diseases

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Interactions

30 interactions

InteractorPartnerSourcesPublicationsLink
PDIA6_HUMANMTR1A_HUMANBioGRID, HPRD, IntAct17215244 26514267 details
PDIA6_HUMANMTR1B_HUMANBioGRID, HPRD, IntAct17215244 26514267 details
PDIA6_HUMANPRDX4_HUMANMINT21057456 details
PDIA6_HUMANCASP8_HUMANBioGRID, IntAct21988832 details
PDIA6_HUMANCSK21_HUMANBioGRID, IntAct22113938 details
PDIA6_HUMANAT132_HUMANBioGRID, IntAct22645275 details
PDIA6_HUMANSGTB_HUMANBioGRID, IntAct32296183 details
PDIA6_HUMANGET3_HUMANBioGRID, IntAct32296183 details
PDIA6_HUMANMC4R_HUMANBioGRID, MINT28298427 details
PDIA6_HUMANA4_HUMANIntAct32814053 details
PDIA6_HUMANCLN8_HUMANBioGRID23142642 details
PDIA6_HUMANVKOR1_HUMANBioGRID21103663 details
PDIA6_HUMANLEG9_HUMANBioGRID21670307 31995728 details
PDIA6_HUMANUBE3A_HUMANBioGRID26506232 details
PDIA6_HUMANTRI14_HUMANBioGRID29053956 details
PDIA6_HUMANS22A2_HUMANBioGRID31318583 details
PDIA6_HUMANOGT1_HUMANBioGRID32994395 details
PDIA6_HUMANTRAF6_HUMANIntAct17353931 details
PDIA6_HUMANAAKB1_HUMANIntAct17353931 details
PDIA6_HUMANNDKB_HUMANBioGRID, IntAct17353931 details
PDIA6_HUMANRL37L_HUMANIntAct30021884 details
PDIA6_HUMANFYN_HUMANIntAct31413325 details
PDIA6_HUMANHDAC5_HUMANBioGRID21081666 details
PDIA6_HUMANGLUT4_HUMANBioGRID, HPRD16396496 details
PDIA6_HUMANMET23_HUMANBioGRID23349634 details
PDIA6_HUMANU2AF2_HUMANBioGRID26641092 details
PDIA6_HUMANHDAC6_HUMANBioGRID29278704 details
PDIA6_HUMANFBLN3_HUMANBioGRID27777122 details
PDIA6_HUMANERN1_HUMANBioGRID32149426 details
PDIA6_HUMANSUMO4_HUMANHPRD16236267 details