Entity Details

Primary name PMVK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15126
EntryNamePMVK_HUMAN
FullNamePhosphomevalonate kinase
TaxID9606
Evidenceevidence at protein level
Length192
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPMVK

GO terms

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GOName
GO:0004631 phosphomevalonate kinase activity
GO:0005524 ATP binding
GO:0005777 peroxisome
GO:0005829 cytosol
GO:0006695 cholesterol biosynthetic process
GO:0016020 membrane
GO:0016126 sterol biosynthetic process
GO:0019216 regulation of lipid metabolic process
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway
GO:0070062 extracellular exosome
GO:0070723 response to cholesterol

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR005919 Higher eukaryotic phosphomevalonate kinaseFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
PMVK_HUMANDDT4L_HUMANBioGRID, IntAct32296183 details
PMVK_HUMANZN177_HUMANBioGRID, IntAct32296183 details
PMVK_HUMANMCPH1_HUMANBioGRID29150431 details