Entity Details

Primary name IL6ST
Entity type gene
Source Source Link

Details

PrimaryID3572
RefseqGene
SymbolIL6ST
Nameinterleukin 6 cytokine family signal transducer
Chromosome5
Location5q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsIL6RB_HUMAN

GO terms

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GOName
GO:0002675 positive regulation of acute inflammatory response
GO:0002821 positive regulation of adaptive immune response
GO:0004896 cytokine receptor activity
GO:0004897 ciliary neurotrophic factor receptor activity
GO:0004921 interleukin-11 receptor activity
GO:0005127 ciliary neurotrophic factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005896 interleukin-6 receptor complex
GO:0005900 oncostatin-M receptor complex
GO:0005977 glycogen metabolic process
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0016020 membrane
GO:0016032 viral process
GO:0019221 cytokine-mediated signaling pathway
GO:0019838 growth factor binding
GO:0019955 cytokine binding
GO:0019970 interleukin-11 binding
GO:0030425 dendrite
GO:0034097 response to cytokine
GO:0038165 oncostatin-M-mediated signaling pathway
GO:0042102 positive regulation of T cell proliferation
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043066 negative regulation of apoptotic process
GO:0043235 receptor complex
GO:0045509 interleukin-27 receptor activity
GO:0045669 positive regulation of osteoblast differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0048711 positive regulation of astrocyte differentiation
GO:0048861 leukemia inhibitory factor signaling pathway
GO:0060576 intestinal epithelial cell development
GO:0070062 extracellular exosome
GO:0070102 interleukin-6-mediated signaling pathway
GO:0070104 negative regulation of interleukin-6-mediated signaling pathway
GO:0070106 interleukin-27-mediated signaling pathway
GO:0070110 ciliary neurotrophic factor receptor complex
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway
GO:0070757 interleukin-35-mediated signaling pathway

Diseases

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Interactions

47 interactions

InteractorPartnerSourcesPublicationsLink
IL6STCNTFHPRD, IntAct, MINT12643274 16051226 18775332 details
IL6STOSMBioGRID, HPRD, IntAct, MINT16051226 26186194 28514442 8999038 details
IL6STLIFHPRD, IntAct, MINT12707269 14527405 16051226 details
IL6STSTAT1MINT8662591 details
IL6STCMYA5BioGRID, IntAct23414517 details
IL6STMAGEA11BioGRID, IntAct25416956 32296183 details
IL6STKCNIP3BioGRID, IntAct25416956 32296183 details
IL6STSGTABioGRID, IntAct32296183 details
IL6STSGTBBioGRID, IntAct25416956 29892012 32296183 details
IL6STKCNIP1BioGRID, IntAct32296183 details
IL6STJAK1BioGRID, DIP, HPRD11468294 11742534 21220115 9388212 details
IL6STTLE1BioGRID, HPRD12030375 details
IL6STCNTFRBioGRID, HPRD11285233 12707266 details
IL6STPTPN11BioGRID, HPRD10777583 10946280 12403768 9195977 9388212 9794795 details
IL6STSOCS3BioGRID, HPRD10777583 10946280 12403768 24438103 32548823 details
IL6STCDK9BioGRID, HPRD12386808 details
IL6STVAV1BioGRID, HPRD9013873 details
IL6STGRB2BioGRID9013873 details
IL6STSHC1BioGRID9126968 details
IL6STUBQLN1BioGRID25416956 details
IL6STFBXO2BioGRID32549792 details
IL6STIL6HPRD, IntAct12829785 14557255 18775332 details
IL6STIL6RBioGRID, HPRD, UniProt11238858 2788034 details
IL6STIL6STDIP, HPRD, IntAct11251120 19020503 24501689 details
IL6STOSMRBioGRID, HPRD, IntAct24501689 8999038 9188471 details
IL6STARBioGRID, HPRD15129430 details
IL6STLIFRBioGRID, HPRD12047380 8999038 details
IL6STHCKBioGRID, HPRD11689697 details
IL6STERBB2BioGRID, HPRD11821958 details
IL6STERBB3BioGRID, HPRD11821958 details
IL6STJAK2BioGRID9388212 details
IL6STTYK2BioGRID, HPRD9388212 details
IL6STPRKCDBioGRID, HPRD12361954 details
IL6STSTAT3BioGRID, HPRD12361954 details
IL6STPIK3R1BioGRID10579793 details
IL6STPTPN6BioGRID, HPRD10800945 details
IL6STCTF1HPRD11834704 details
IL6STPIK3CGHPRD10579793 details
IL6STIL31RAHPRD14504285 15184896 details
IL6STPLAURHPRD9353320 details
IL6STPYCARDBioGRID, HPIDb24407287 details
IL6STCDH1BioGRID25468996 details
IL6STKRASBioGRID30194290 30639242 details
IL6STNRASBioGRID30194290 details
IL6STSOX18IntAct29408481 details
IL6STTRIM25BioGRID29117863 details
IL6STDDX58BioGRID32513696 details