Entity Details

Primary name IRF6
Entity type gene
Source Source Link

Details

PrimaryID3664
RefseqGeneNG_007081
SymbolIRF6
Nameinterferon regulatory factor 6
Chromosome1
Location1q32.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsIRF6_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002376 immune system process
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008285 negative regulation of cell population proliferation
GO:0030054 cell junction
GO:0030216 keratinocyte differentiation
GO:0043565 sequence-specific DNA binding
GO:0043616 keratinocyte proliferation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048468 cell development
GO:0060021 roof of mouth development
GO:0060173 limb development
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0060644 mammary gland epithelial cell differentiation
GO:0070062 extracellular exosome
GO:1904888 cranial skeletal system development
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
IRF6IRF8BioGRID, IntAct21903422 details
IRF6TLX2BioGRID, IntAct20211142 details
IRF6RFX3BioGRID, IntAct20211142 details
IRF6IRF5BioGRID, IntAct21903422 details
IRF6BNC2BioGRID, IntAct21903422 details
IRF6ZFP36L2BioGRID29449217 details