Entity Details

Primary name PTN14_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15678
EntryNamePTN14_HUMAN
FullNameTyrosine-protein phosphatase non-receptor type 14
TaxID9606
Evidenceevidence at protein level
Length1187
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPTPN14

GO terms

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GOName
GO:0001946 lymphangiogenesis
GO:0003712 transcription coregulator activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0006470 protein dephosphorylation
GO:0008285 negative regulation of cell population proliferation
GO:0030971 receptor tyrosine kinase binding
GO:0046825 regulation of protein export from nucleus
GO:0071345 cellular response to cytokine stimulus

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000299 FERM domainDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR014392 Protein-tyrosine phosphatase, non-receptor type-14/21FamilyFamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR018979 FERM, N-terminalDomainDomain
IPR018980 FERM, C-terminal PH-like domainDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR041782 PTPN14/21, FERM domain C-lobeDomainDomain

Diseases

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Interactions

59 interactions

InteractorPartnerSourcesPublicationsLink
PTN14_HUMANYAP1_HUMANBioGRID, DIP, IntAct, MINT22948661 24255178 24366813 25283809 25751139 25796446 27432908 27684187 28514442 28675297 32292505 details
PTN14_HUMANTRIP6_HUMANBioGRID, IntAct32296183 details
PTN14_HUMANAMOT_HUMANBioGRID22948661 27432908 32296183 34079125 details
PTN14_HUMANKIBRA_HUMANBioGRID, IntAct22948661 24366813 25023289 27432908 28514442 28675297 28720576 details
PTN14_HUMAN1433B_HUMANBioGRID, IntAct22948661 24255178 27432908 28514442 details
PTN14_HUMANLATS1_HUMANBioGRID, IntAct24255178 25023289 34079125 details
PTN14_HUMANDCLK1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANSI1L1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANMAST3_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANSRGP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANGGYF1_HUMANIntActunassigned1312 details
PTN14_HUMANNF1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANHDAC4_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANZN638_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANIF4E2_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANKSR1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANDEN4C_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANSPD2A_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANSYDE1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANDEN1A_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANSRS12_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANMAGI1_HUMANBioGRID, IntAct27173435 28514442 unassigned1312 details
PTN14_HUMANTESK2_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANRTKN_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANKI13B_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANINP5E_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANLRFN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANCING_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANLIMA1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANZBT21_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANPPM1H_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANCBY1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMANKCTD3_HUMANBioGRID, IntAct27173435 unassigned1312 details
PTN14_HUMAN1433G_HUMANBioGRID, HPRD, IntAct15324660 27432908 28514442 details
PTN14_HUMANCTNB1_HUMANBioGRID, HPRD12808048 details
PTN14_HUMANCTNA1_HUMANBioGRID12808048 details
PTN14_HUMANZO1_HUMANBioGRID, HPRD12808048 details
PTN14_HUMANPLAK_HUMANBioGRID, HPRD12808048 details
PTN14_HUMANPTEN_HUMANBioGRID15717329 details
PTN14_HUMAN1433E_HUMANBioGRID17979178 22948661 details
PTN14_HUMANCUL2_HUMANBioGRID22948661 27432908 details
PTN14_HUMANPLK1_HUMANBioGRID22948661 27432908 details
PTN14_HUMANDDB1_HUMANBioGRID22948661 details
PTN14_HUMAN2AAA_HUMANBioGRID22948661 details
PTN14_HUMAN2ABA_HUMANBioGRID22948661 details
PTN14_HUMAN1433Z_HUMANBioGRID22948661 details
PTN14_HUMANWWC2_HUMANBioGRID22948661 27432908 28675297 details
PTN14_HUMANUBC_HUMANBioGRID22948661 details
PTN14_HUMANCSN4_HUMANBioGRID22948661 27432908 details
PTN14_HUMANSTK3_HUMANBioGRID22948661 27432908 details
PTN14_HUMANLLR1_HUMANBioGRID22948661 27432908 details
PTN14_HUMANWWP1_HUMANBioGRID22948661 27432908 31340145 details
PTN14_HUMANWWP2_HUMANBioGRID22948661 25071155 31048545 details
PTN14_HUMANKC1D_HUMANBioGRID22948661 details
PTN14_HUMANVHL_HUMANBioGRID22948661 details
PTN14_HUMANRC3H2_HUMANBioGRID30209976 details
PTN14_HUMANSMAG2_HUMANBioGRID29395067 details
PTN14_HUMANSOCS7_HUMANBioGRID32978373 details
PTN14_HUMANCTNA2_HUMANHPRD12808048 details