Entity Details

Primary name NSDHL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15738
EntryNameNSDHL_HUMAN
FullNameSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
TaxID9606
Evidenceevidence at protein level
Length373
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesNSDHL

GO terms

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GOName
GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
GO:0001942 hair follicle development
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005811 lipid droplet
GO:0006695 cholesterol biosynthetic process
GO:0007224 smoothened signaling pathway
GO:0008203 cholesterol metabolic process
GO:0016021 integral component of membrane
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047012 sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity
GO:0060716 labyrinthine layer blood vessel development
GO:0102175 3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity
GO:0103066 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity
GO:0103067 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Lipid droplet

Domains

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DomainNameCategoryType
IPR002225 3-beta hydroxysteroid dehydrogenase/isomeraseDomainDomain
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule