Entity Details

Primary name MTHFR
Entity type gene
Source Source Link

Details

PrimaryID4524
RefseqGeneNG_013351
SymbolMTHFR
Namemethylenetetrahydrofolate reductase
Chromosome1
Location1p36.22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-07-20
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsMTHR_HUMAN

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0001843 neural tube closure
GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity
GO:0005829 cytosol
GO:0006555 methionine metabolic process
GO:0009086 methionine biosynthetic process
GO:0031060 regulation of histone methylation
GO:0033274 response to vitamin B2
GO:0035999 tetrahydrofolate interconversion
GO:0042493 response to drug
GO:0043200 response to amino acid
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0046500 S-adenosylmethionine metabolic process
GO:0046655 folic acid metabolic process
GO:0050660 flavin adenine dinucleotide binding
GO:0050661 NADP binding
GO:0050667 homocysteine metabolic process
GO:0051593 response to folic acid
GO:0070555 response to interleukin-1
GO:0070829 heterochromatin maintenance
GO:0071949 FAD binding
GO:0072341 modified amino acid binding
GO:0106312 methylenetetrahydrofolate reductase NADH activity
GO:0106313 methylenetetrahydrofolate reductase NADPH activity

Diseases

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