Entity Details

Primary name MYL4
Entity type gene
Source Source Link

Details

PrimaryID4635
RefseqGeneNG_052847
SymbolMYL4
Namemyosin light chain 4
Chromosome17
Location17q21.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1988-10-24
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMYL4_HUMAN

GO terms

Show/Hide Table
GOName
GO:0002026 regulation of the force of heart contraction
GO:0003785 actin monomer binding
GO:0005509 calcium ion binding
GO:0005829 cytosol
GO:0016459 myosin complex
GO:0030049 muscle filament sliding
GO:0031672 A band
GO:0032038 myosin II heavy chain binding
GO:0032781 positive regulation of ATPase activity
GO:0051015 actin filament binding
GO:0060048 cardiac muscle contraction

Diseases

Show/Hide Table
Disease IDSourceNameDescription
617280 OMIMAtrial fibrillation, familial, 18 (ATFB18)A familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. The disease is caused by variants affecting the gene represented in this entry.

Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
MYL4PYROXD2BioGRID, IntAct21988832 details
MYL4ALBBioGRID, IntAct15174051 details
MYL4VCAM1BioGRID, IntAct19738201 22623428 details
MYL4FN1BioGRID, IntAct19738201 details
MYL4ITGA4BioGRID22623428 details
MYL4AGO2BioGRID25681748 details
MYL4NR2C2BioGRID30463901 details
MYL4CUL5BioGRID31253590 details