Entity Details

Primary name NCF2
Entity type gene
Source Source Link

Details

PrimaryID4688
RefseqGeneNG_007267
SymbolNCF2
Nameneutrophil cytosolic factor 2
Chromosome1
Location1q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNCF2_HUMAN

GO terms

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GOName
GO:0001669 acrosomal vesicle
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005829 cytosol
GO:0006801 superoxide metabolic process
GO:0006909 phagocytosis
GO:0006968 cellular defense response
GO:0008022 protein C-terminus binding
GO:0009055 electron transfer activity
GO:0016020 membrane
GO:0016175 superoxide-generating NAD(P)H oxidase activity
GO:0016176 superoxide-generating NADPH oxidase activator activity
GO:0031267 small GTPase binding
GO:0032010 phagolysosome
GO:0034599 cellular response to oxidative stress
GO:0042554 superoxide anion generation
GO:0043020 NADPH oxidase complex
GO:0045087 innate immune response
GO:0045454 cell redox homeostasis
GO:0045730 respiratory burst
GO:0048010 vascular endothelial growth factor receptor signaling pathway

Diseases

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Interactions

30 interactions

InteractorPartnerSourcesPublicationsLink
NCF2NCF4BioGRID, HPRD, IntAct, MINT10486263 10672014 11483497 11796733 11893732 12813044 12887891 16297854 16782902 9083043 details
NCF2CDC42BioGRID, HPRD, MINT11090627 7738010 9642115 details
NCF2RAC1BioGRID, HPRD, IntAct, MINT11090627 11896062 25301945 25416956 7738010 8036496 9255350 9624165 9642115 details
NCF2RAC2BioGRID, HPRD, MINT11090627 9624165 9642115 details
NCF2NCF1BioGRID, HPRD, IntAct, MINT10486263 11248021 11733522 11796733 11893732 12169629 15657040 16052631 16297854 16782902 19129478 32296183 7938008 9121467 details
NCF2KIFAP3BioGRID, IntAct, MINT21516116 25416956 25910212 26871637 31515488 32296183 details
NCF2GOLGA2BioGRID, IntAct25416956 25910212 26871637 details
NCF2PRKCDIntAct15591124 details
NCF2PRDX6BioGRID, HPRD12121978 details
NCF2CYBABioGRID, HPRD11248021 11733522 11893732 11917128 details
NCF2SYTL1BioGRID, HPRD11278853 details
NCF2PRKDCBioGRID9914162 details
NCF2S100A8BioGRID, HPRD15642721 details
NCF2S100A9BioGRID15642721 details
NCF2PLA2G4ABioGRID16844764 18765662 details
NCF2AKT1BioGRID12515553 details
NCF2CYBBBioGRID, HPRD11248021 11893732 11917128 15260500 details
NCF2GNAI2BioGRID, MINT16782902 details
NCF2GNB1BioGRID, MINT16782902 details
NCF2TRAF4BioGRID16052631 details
NCF2GNAI1BioGRID16782902 details
NCF2GNAI3BioGRID16782902 details
NCF2HSPA8IntAct25910212 details
NCF2HSP90AB1IntAct25910212 details
NCF2CAMSAP3BioGRID, IntAct28514442 details
NCF2USP47BioGRID, IntAct28514442 details
NCF2BPGMBioGRID, IntAct28514442 details
NCF2TBC1D4BioGRID, IntAct28514442 details
NCF2TARDBPBioGRID, IntAct28514442 details
NCF2DDX21BioGRID, IntAct30021884 details