Entity Details

Primary name PDYN
Entity type gene
Source Source Link

Details

PrimaryID5173
RefseqGeneNG_028027
SymbolPDYN
Nameprodynorphin
Chromosome20
Location20p13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1988-06-01
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPDYN_HUMAN

GO terms

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GOName
GO:0001515 opioid peptide activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007600 sensory perception
GO:0030425 dendrite
GO:0031628 opioid receptor binding
GO:0043025 neuronal cell body
GO:0043679 axon terminus

Diseases

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Disease IDSourceNameDescription
610245 OMIMSpinocerebellar ataxia 23 (SCA23)Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA23 is an adult-onset autosomal dominant form characterized by slowly progressive gait and limb ataxia, with variable additional features, including peripheral neuropathy and dysarthria. The disease is caused by variants affecting the gene represented in this entry.

Interactions

10 interactions