Entity Details

Primary name OCLN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16625
EntryNameOCLN_HUMAN
FullNameOccludin
TaxID9606
Evidenceevidence at protein level
Length522
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesOCLN

GO terms

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GOName
GO:0001933 negative regulation of protein phosphorylation
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005923 bicellular tight junction
GO:0010592 positive regulation of lamellipodium assembly
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010827 regulation of glucose transmembrane transport
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016327 apicolateral plasma membrane
GO:0016328 lateral plasma membrane
GO:0019904 protein domain specific binding
GO:0030054 cell junction
GO:0030139 endocytic vesicle
GO:0031116 positive regulation of microtubule polymerization
GO:0031252 cell leading edge
GO:0031410 cytoplasmic vesicle
GO:0032991 protein-containing complex
GO:0035633 maintenance of blood-brain barrier
GO:0045216 cell-cell junction organization
GO:0046326 positive regulation of glucose import
GO:0065003 protein-containing complex assembly
GO:0070160 tight junction
GO:0070673 response to interleukin-18
GO:0070830 bicellular tight junction assembly
GO:0071356 cellular response to tumor necrosis factor
GO:0090303 positive regulation of wound healing
GO:1902463 protein localization to cell leading edge
GO:1905605 positive regulation of blood-brain barrier permeability
GO:2000810 regulation of bicellular tight junction assembly

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR002958 OccludinFamilyFamily
IPR008253 Marvel domainDomainDomain
IPR010844 Occludin homology domainDomainDomain
IPR031176 ELL/occludin familyFamilyFamily
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
OCLN_HUMANKC1E_HUMANBioGRID, HPRD, IntAct, MINT16616143 25241761 28514442 details
OCLN_HUMANULK1_HUMANBioGRID, MINT16616143 details
OCLN_HUMANSNW1_HUMANBioGRID, MINT16616143 details
OCLN_HUMANKC1A_HUMANBioGRID, HPRD, MINT16616143 details
OCLN_HUMANZO1_HUMANBioGRID, HPRD, Molecular Connections10575001 10601346 11700038 12169098 18662404 19017651 23758859 26090670 33100129 34079125 7798316 9792688 details
OCLN_HUMANSYNE4_HUMANBioGRID, IntAct25416956 26186194 28514442 details
OCLN_HUMANCLC7A_HUMANBioGRID, IntAct25416956 details
OCLN_HUMANGPX8_HUMANBioGRID, IntAct32296183 details
OCLN_HUMANCATS_HUMANDIP25086747 details
OCLN_HUMANKPCL_HUMANDIP19114660 details
OCLN_HUMANDYN2_HUMANIntAct32814053 details
OCLN_HUMANNDUV2_HUMANIntAct32814053 details
OCLN_HUMANZO2_HUMANBioGRID, HPRD10026224 10575001 14512431 23758859 34079125 details
OCLN_HUMANITCH_HUMANBioGRID, HPRD11782481 19478092 33100129 34079125 details
OCLN_HUMANTNAP3_HUMANBioGRID22031828 details
OCLN_HUMANFATE1_HUMANBioGRID21516116 details
OCLN_HUMANPTN2_HUMANBioGRID26090670 details
OCLN_HUMANCSK21_HUMANBioGRID23758859 details
OCLN_HUMANOCLN_HUMANBioGRID, HPRD10026224 23758859 details
OCLN_HUMANOGT1_HUMANBioGRID32994395 details
OCLN_HUMANPLS1_HUMANMINT21806988 details
OCLN_HUMANNED4L_HUMANBioGRID, IntAct20504882 28514442 details
OCLN_HUMANRAB8B_HUMANBioGRID12639940 details
OCLN_HUMANYES_HUMANBioGRID, HPRD11950934 34079125 details
OCLN_HUMANCXB1_HUMANBioGRID, HPRD10581193 details
OCLN_HUMANEPN1_HUMANBioGRID19478092 details
OCLN_HUMANEPS15_HUMANBioGRID19478092 details
OCLN_HUMANHGS_HUMANBioGRID19478092 details
OCLN_HUMANTGFR1_HUMANBioGRID, HPRD15761153 details
OCLN_HUMANTGFR2_HUMANBioGRID15761153 details
OCLN_HUMANKPCA_HUMANHPRD11502742 details
OCLN_HUMANKPCB_HUMANHPRD11502742 details
OCLN_HUMANKPCG_HUMANHPRD11502742 details
OCLN_HUMANCSK2B_HUMANHPRD12804768 details
OCLN_HUMANSMAD4_HUMANHPRD15761153 details
OCLN_HUMANSMUF1_HUMANHPRD15761153 details
OCLN_HUMANACTS_HUMANHPRD10575001 9792688 details