Entity Details

Primary name NPLOC4
Entity type gene
Source Source Link

Details

PrimaryID55666
RefseqGene
SymbolNPLOC4
NameNPL4 homolog, ubiquitin recognition factor
Chromosome17
Location17q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNPL4_HUMAN

GO terms

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GOName
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007030 Golgi organization
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030970 retrograde protein transport, ER to cytosol
GO:0031625 ubiquitin protein ligase binding
GO:0032480 negative regulation of type I interferon production
GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex
GO:0036501 UFD1-NPL4 complex
GO:0039536 negative regulation of RIG-I signaling pathway
GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network
GO:0043130 ubiquitin binding
GO:0046872 metal ion binding
GO:0070987 error-free translesion synthesis

Diseases

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Interactions

137 interactions

InteractorPartnerSourcesPublicationsLink
NPLOC4UBCBioGRID, MINT12644454 16196087 17070805 17550899 25752573 28190767 28525741 details
NPLOC4VCPBioGRID, DIP, IntAct, MINT15371428 16234241 17872946 18586029 18775313 20414249 21645854 23293021 23333620 26389662 26549226 27226613 27762274 27913212 28320958 28443643 29540532 29599191 30335548 30344098 31623962 32814053 details
NPLOC4UFD1BioGRID, DIP, HPRD, IntAct, MINT11574150 15371428 16322459 17202270 18586029 18775313 20414249 21645854 22939629 24248593 26344197 26389662 28320958 32296183 details
NPLOC4VPS26BBioGRID, IntAct32296183 details
NPLOC4TGFBR2BioGRID, IntAct28443643 32814053 details
NPLOC4GZMKBioGRID20876349 details
NPLOC4RAF1BioGRID16364241 details
NPLOC4MAP3K1BioGRID25260751 details
NPLOC4ERCC6BioGRID31722399 details
NPLOC4CDC42BioGRID31478661 details
NPLOC4FAF1BioGRID, DIP, IntAct18775313 21645854 21914798 23293021 26389662 28443643 details
NPLOC4SVIPBioGRID17872946 details
NPLOC4SELENOSBioGRID17872946 details
NPLOC4NSFL1CBioGRID18775313 26389662 details
NPLOC4UBXN11BioGRID18775313 details
NPLOC4ASPSCR1BioGRID18775313 26389662 details
NPLOC4AMFRBioGRID21636303 32614325 details
NPLOC4SPRTNBioGRID23042607 details
NPLOC4UBXN6BioGRID22337587 details
NPLOC4NFKBIABioGRID24248593 details
NPLOC4CDC25ABioGRID24429874 details
NPLOC4BTRCBioGRID24429874 details
NPLOC4ZFAND2BBioGRID24160817 details
NPLOC4IFT74BioGRID26389662 details
NPLOC4TTC26BioGRID26389662 details
NPLOC4GLULBioGRID28320958 details
NPLOC4SMURF1BioGRID30335548 details
NPLOC4DXOBioGRID31164795 details
NPLOC4ST7BioGRID29395067 details
NPLOC4FAF2BioGRID, IntAct18775313 26389662 details
NPLOC4UBXN7BioGRID, IntAct18775313 26389662 details
NPLOC4UBXN1BioGRID, IntAct18775313 details
NPLOC4UBXN8BioGRID, IntAct18775313 details
NPLOC4UBXN10BioGRID, IntAct18775313 26389662 details
NPLOC4USP13BioGRID, IntAct19615732 details
NPLOC4VCPIP1BioGRID, IntAct19615732 26389662 details
NPLOC4UBL4ABioGRID, IntAct19615732 details
NPLOC4E2F3MINT22157815 details
NPLOC4DCTN1BioGRID, IntAct26638075 details
NPLOC4CEP128BioGRID, IntAct26638075 details
NPLOC4KCNC4BioGRID, IntAct28514442 details
NPLOC4FAM189BBioGRID, IntAct28514442 details
NPLOC4SLC17A2BioGRID, IntAct28514442 details
NPLOC4KDELR1BioGRID, IntAct28514442 details
NPLOC4ATG9ABioGRID, IntAct28514442 details
NPLOC4ALG10BBioGRID, IntAct28514442 details
NPLOC4KCNK16BioGRID, IntAct26186194 28514442 details
NPLOC4FADS3BioGRID, IntAct28514442 details
NPLOC4CYP19A1BioGRID, IntAct28514442 details
NPLOC4TRIM13BioGRID, IntAct28514442 details
NPLOC4PSEN2BioGRID, IntAct28514442 details
NPLOC4CANXBioGRID, IntAct29568061 details
NPLOC4P2RY6BioGRID, IntAct30833792 details
NPLOC4HNRNPLBioGRID22939629 26344197 28611215 details
NPLOC4HNRNPRBioGRID22939629 details
NPLOC4FLOT1BioGRID22939629 details
NPLOC4MRPL19BioGRID22939629 details
NPLOC4MRPS9BioGRID22939629 details
NPLOC4MTPNBioGRID22939629 26344197 details
NPLOC4LMNABioGRID22412018 details
NPLOC4ADRB2BioGRID23798571 details
NPLOC4HECW2BioGRID24163370 details
NPLOC4ADSLBioGRID22863883 details
NPLOC4CBSBioGRID22863883 details
NPLOC4DR1BioGRID22863883 details
NPLOC4EIF4A3BioGRID22863883 details
NPLOC4DNAAF5BioGRID22863883 details
NPLOC4METTL1BioGRID22863883 details
NPLOC4ARMC9BioGRID22863883 details
NPLOC4DPP9BioGRID22863883 details
NPLOC4FKBP10BioGRID22863883 details
NPLOC4FNTBBioGRID22863883 details
NPLOC4LPPBioGRID22863883 details
NPLOC4PDLIM5BioGRID22863883 details
NPLOC4PKMBioGRID22863883 details
NPLOC4RPRD1ABioGRID22863883 details
NPLOC4RPRD1BBioGRID22863883 details
NPLOC4SURF2BioGRID22863883 details
NPLOC4UFM1BioGRID22863883 details
NPLOC4PDE12BioGRID22863883 details
NPLOC4PLIN3BioGRID22863883 details
NPLOC4RAD23BBioGRID22863883 details
NPLOC4SAE1BioGRID22863883 details
NPLOC4SRP14BioGRID22863883 details
NPLOC4SSBBioGRID22863883 details
NPLOC4UBA2BioGRID22863883 details
NPLOC4UBE3ABioGRID22863883 details
NPLOC4UBQLN2BioGRID22863883 details
NPLOC4WDR4BioGRID22863883 details
NPLOC4YOD1BioGRID19818707 details
NPLOC4EZH2BioGRID24457600 details
NPLOC4ETNK2BioGRID26186194 details
NPLOC4TMEM62BioGRID26186194 details
NPLOC4SLC38A6BioGRID26186194 details
NPLOC4CD2APBioGRID26344197 details
NPLOC4NDUFS3BioGRID26344197 details
NPLOC4ASNSBioGRID26344197 details
NPLOC4CAP1BioGRID26344197 details
NPLOC4FUSBioGRID26344197 details
NPLOC4GARS1BioGRID26344197 details
NPLOC4HNRNPKBioGRID26344197 details
NPLOC4MTMR12BioGRID26344197 details
NPLOC4PTPRFBioGRID26344197 details
NPLOC4RRM2BioGRID26344197 details
NPLOC4SH3KBP1BioGRID26344197 details
NPLOC4UBA1BioGRID26344197 details
NPLOC4PICALMBioGRID26344197 details
NPLOC4NTRK1BioGRID25921289 details
NPLOC4MCM2BioGRID25963833 details
NPLOC4ADKBioGRID26389662 details
NPLOC4UBAC2BioGRID26389662 details
NPLOC4PYCR2BioGRID26389662 details
NPLOC4TRIP10BioGRID26389662 details
NPLOC4TRIM14BioGRID29053956 details
NPLOC4EGLN3BioGRID26972000 details
NPLOC4EFTUD2BioGRID28515276 details
NPLOC4RECQL4BioGRID29229926 details
NPLOC4IFITM3BioGRID30833792 details
NPLOC4PTPRHBioGRID28675297 details
NPLOC4RHBDD1BioGRID31177093 details
NPLOC4PLEKHA4BioGRID31091453 details
NPLOC4KCTD10BioGRID31280863 details
NPLOC4PINK1BioGRID31300519 details
NPLOC4SEC61BBioGRID32788342 34079125 details
NPLOC4BRD4BioGRID32416067 details
NPLOC4RNF185BioGRID32614325 details
NPLOC4TP53BioGRID32807901 details
NPLOC4BCAP31BioGRID34079125 details
NPLOC4CYP2C9BioGRID34079125 details
NPLOC4GJD3BioGRID34079125 details
NPLOC4METTL7ABioGRID34079125 details
NPLOC4PXMP2BioGRID34079125 details
NPLOC4ELAVL1BioGRID19322201 details
NPLOC4ENO1BioGRID22658674 details
NPLOC4MOV10BioGRID22658674 details
NPLOC4NXF1BioGRID22658674 details
NPLOC4TRIM25BioGRID29117863 details