Entity Details

Primary name EDEM2
Entity type gene
Source Source Link

Details

PrimaryID55741
RefseqGene
SymbolEDEM2
NameER degradation enhancing alpha-mannosidase like protein 2
Chromosome20
Location20q11.22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsEDEM2_HUMAN

GO terms

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GOName
GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 calcium ion binding
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005975 carbohydrate metabolic process
GO:0006986 response to unfolded protein
GO:0016020 membrane
GO:0019082 viral protein processing
GO:0036509 trimming of terminal mannose on B branch
GO:0036510 trimming of terminal mannose on C branch
GO:0036511 trimming of first mannose on A branch
GO:0036512 trimming of second mannose on A branch
GO:0044322 endoplasmic reticulum quality control compartment
GO:0097466 ubiquitin-dependent glycoprotein ERAD pathway
GO:1904154 positive regulation of retrograde protein transport, ER to cytosol
GO:1904382 mannose trimming involved in glycoprotein ERAD pathway

Diseases

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Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
EDEM2RPS3ABioGRID, HPRD, IntAct16169070 details
EDEM2SEL1LBioGRID24910992 details
EDEM2CANXBioGRID24910992 details
EDEM2SHHBioGRID24910992 details
EDEM2ADGRG5BioGRID, IntAct28514442 details
EDEM2TMPRSS11BBioGRID, IntAct28514442 details
EDEM2TMEM30ABioGRID, IntAct26186194 28514442 details
EDEM2BLKBioGRID, IntAct28514442 details
EDEM2B3GNT2BioGRID, IntAct28514442 details
EDEM2SLC38A10BioGRID, IntAct28514442 details
EDEM2SFXN3BioGRID, IntAct28514442 details
EDEM2TIMM29BioGRID, IntAct28514442 details
EDEM2TVP23C-CDRT4IntAct28514442 details
EDEM2TVP23CBioGRID, IntAct28514442 details
EDEM2OMA1BioGRID, IntAct28514442 details
EDEM2SLC16A10BioGRID, IntAct28514442 details
EDEM2SLC35B2BioGRID, IntAct28514442 details
EDEM2UHMK1BioGRID, IntAct28514442 details
EDEM2MCUBioGRID, IntAct28514442 details
EDEM2TXNDC11BioGRID, IntAct28514442 details
EDEM2C3orf33BioGRID, IntAct28514442 details
EDEM2TMTC4BioGRID, IntAct28514442 details
EDEM2SURF1BioGRID, IntAct28514442 details
EDEM2OS9BioGRID, IntAct28514442 details
EDEM2MCL1BioGRID, IntAct28514442 details
EDEM2SLC25A16BioGRID, IntAct28514442 details
EDEM2HACD1BioGRID, IntAct28514442 details
EDEM2CYTIPBioGRID, IntAct26186194 28514442 details
EDEM2TAFAZZINBioGRID, IntAct26186194 28514442 details
EDEM2LYPD4BioGRID, IntAct28514442 details
EDEM2MXD3BioGRID, IntAct28514442 details
EDEM2LYZL1BioGRID, IntAct28514442 details
EDEM2CHST8BioGRID, IntAct26186194 28514442 details
EDEM2PSMC5BioGRID, IntAct28514442 details
EDEM2CLUBioGRID, IntAct28514442 details
EDEM2HEPACAM2BioGRID, IntAct26186194 28514442 details
EDEM2BRINP3BioGRID, IntAct28514442 details
EDEM2NAAABioGRID, IntAct26186194 28514442 details
EDEM2THBS2BioGRID, IntAct28514442 details
EDEM2C8GBioGRID, IntAct28514442 details
EDEM2OLFM1BioGRID, IntAct26186194 28514442 details
EDEM2BRINP2BioGRID, IntAct28514442 details
EDEM2FBLN7BioGRID, IntAct26186194 28514442 details
EDEM2ANGPTL7BioGRID, IntAct28514442 details
EDEM2DCTBioGRID, IntAct28514442 details
EDEM2HLA-EBioGRID26186194 details
EDEM2EDEM3BioGRID28366632 details
EDEM2KCTD10BioGRID31280863 details
EDEM2FAM20CBioGRID32149426 details
EDEM2DDX58BioGRID32513696 details