Entity Details

Primary name SP3
Entity type gene
Source Source Link

Details

PrimaryID6670
RefseqGeneNG_029153
SymbolSP3
NameSp3 transcription factor
Chromosome2
Location2q31.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-24
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSP3_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001503 ossification
GO:0001779 natural killer cell differentiation
GO:0001829 trophectodermal cell differentiation
GO:0001889 liver development
GO:0001892 embryonic placenta development
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0016605 PML body
GO:0017053 transcription repressor complex
GO:0030183 B cell differentiation
GO:0030217 T cell differentiation
GO:0030219 megakaryocyte differentiation
GO:0030224 monocyte differentiation
GO:0030324 lung development
GO:0030851 granulocyte differentiation
GO:0032993 protein-DNA complex
GO:0043353 enucleate erythrocyte differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048596 embryonic camera-type eye morphogenesis
GO:0048706 embryonic skeletal system development
GO:0060136 embryonic process involved in female pregnancy
GO:0060216 definitive hemopoiesis
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

56 interactions

InteractorPartnerSourcesPublicationsLink
SP3STK19BioGRID, HPRD, IntAct14667819 details
SP3GABPABioGRID, HPRD, MINT11237613 details
SP3GCH1BioGRID, IntAct16696853 details
SP3ESR1BioGRID, HPRD, IntAct, UniProt10816575 16651265 31527615 details
SP3HTTIntAct17500595 32814053 details
SP3CIB3BioGRID, IntAct32296183 details
SP3PHF21ABioGRID, IntAct32296183 details
SP3SPANXN2BioGRID, IntAct32296183 details
SP3SNRPBBioGRID, IntAct32296183 details
SP3POGZBioGRID, IntAct32296183 details
SP3LIN54BioGRID, IntAct32296183 details
SP3PIAS1BioGRID, HPRD12356736 details
SP3E2F1BioGRID, HPRD10547281 details
SP3SP1BioGRID, HPRD10825178 11517158 12200149 12414801 15247906 16734381 23825960 9329821 details
SP3NKX3-1BioGRID16201967 details
SP3TP53BioGRID, HPRD12665570 15790310 details
SP3HLTFBioGRID10391891 details
SP3TP73BioGRID15790310 details
SP3VEGFABioGRID15342781 details
SP3AKT1BioGRID15342781 details
SP3RPS20BioGRID15494207 details
SP3UBE2IBioGRID, HPRD12419227 15494207 details
SP3HDAC2BioGRID, HPRD12151407 12176973 17548428 details
SP3RBBP4BioGRID, HPRD12091390 12943729 details
SP3HDAC1BioGRID, HPRD11517158 12176973 12200149 16734381 17548428 17906119 details
SP3SFPQBioGRID19339282 details
SP3DNMT1BioGRID17124180 details
SP3CREBBPBioGRID16734381 details
SP3EP300BioGRID, HPRD11517158 12071960 12200149 16734381 details
SP3CEBPBBioGRID16651265 details
SP3CRXBioGRID15781457 details
SP3ZBTB7BBioGRID17698844 details
SP3MECP2BioGRID20385708 details
SP3RELABioGRID22139845 details
SP3YY1BioGRID21335086 details
SP3PPP1CCBioGRID23401853 details
SP3PTPABioGRID23401853 details
SP3DEAF1BioGRID23825960 details
SP3SUB1BioGRID23825960 details
SP3PMLBioGRID15494207 details
SP3RB1HPRD7732011 details
SP3SUMO1HPRD12419227 details
SP3ZBTB7AHPRD12004059 details
SP3GRIN1HPRD14970236 details
SP3TSHBBioGRID, IntAct28514442 details
SP3TFAP4BioGRID19505873 details
SP3SGCZBioGRID26186194 28514442 details
SP3ADAMTS12BioGRID26186194 details
SP3ITLN1BioGRID26186194 details
SP3B4GALT4BioGRID26186194 details
SP3TMEM25BioGRID26186194 details
SP3PTPRKBioGRID26186194 details
SP3ESR2BioGRID29509190 details
SP3PRKRAIntAct16339759 details
SP3BMFIntAct25321483 details
SP3HNRNPH1BioGRID26760575 details