Entity Details

Primary name TFAP2A
Entity type gene
Source Source Link

Details

PrimaryID7020
RefseqGeneNG_016151
SymbolTFAP2A
Nametranscription factor AP-2 alpha
Chromosome6
Location6p24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAP2A_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001822 kidney development
GO:0003404 optic vesicle morphogenesis
GO:0003409 optic cup structural organization
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007605 sensory perception of sound
GO:0008285 negative regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010842 retina layer formation
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0021559 trigeminal nerve development
GO:0021623 oculomotor nerve formation
GO:0030501 positive regulation of bone mineralization
GO:0035115 embryonic forelimb morphogenesis
GO:0042127 regulation of cell population proliferation
GO:0042472 inner ear morphogenesis
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045595 regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048856 anatomical structure development
GO:0060021 roof of mouth development
GO:0060349 bone morphogenesis
GO:0061029 eyelid development in camera-type eye
GO:0070172 positive regulation of tooth mineralization
GO:0071281 cellular response to iron ion
GO:0140536 nuclear receptor corepressor activity
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000378 negative regulation of reactive oxygen species metabolic process

Diseases

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Interactions

179 interactions

InteractorPartnerSourcesPublicationsLink
TFAP2AUBE2IBioGRID, IntAct12072434 24835590 details
TFAP2AEP300BioGRID, HPRD, IntAct12586840 25669978 details
TFAP2ACITED2BioGRID, HPRD, IntAct11744733 12586840 details
TFAP2ANPM1BioGRID, HPRD, MINT17318229 19074833 details
TFAP2ATNXBIntAct24835590 details
TFAP2AMT2AIntAct24835590 details
TFAP2ALOXL1IntAct24835590 details
TFAP2AIFI27IntAct24835590 details
TFAP2AFHL2IntAct24835590 details
TFAP2AZNF326IntAct24835590 details
TFAP2AZMYM2IntAct24835590 details
TFAP2ATUBB2AIntAct24835590 details
TFAP2ATOX3IntAct24835590 details
TFAP2ATMPRSS5IntAct24835590 details
TFAP2ARPSAIntAct24835590 details
TFAP2AREREIntAct24835590 details
TFAP2APPME1IntAct24835590 details
TFAP2ARANBP9IntAct24835590 details
TFAP2ALAMA5IntAct24835590 details
TFAP2AMPSTIntAct24835590 details
TFAP2AMORN1IntAct24835590 details
TFAP2AMOB3CIntAct24835590 details
TFAP2ALDHAIntAct24835590 details
TFAP2ADBF4BIntAct24835590 details
TFAP2ACPEIntAct24835590 details
TFAP2ACDK5IntAct24835590 details
TFAP2AATP5F1AIntAct24835590 details
TFAP2AC1QCIntAct24835590 details
TFAP2AARSAIntAct24835590 details
TFAP2AFCGBPIntAct24835590 details
TFAP2AALDH16A1IntAct24835590 details
TFAP2ACCN5IntAct24835590 details
TFAP2AFBLN1IntAct24835590 details
TFAP2AIFI27L2IntAct24835590 details
TFAP2AEYA2BioGRID, IntAct24835590 27880917 details
TFAP2ADPP7IntAct24835590 details
TFAP2ACOL1A1IntAct24835590 details
TFAP2ACOL1A2IntAct24835590 details
TFAP2ACOL15A1IntAct24835590 details
TFAP2ACCDC80IntAct24835590 details
TFAP2ACFHIntAct24835590 details
TFAP2AZNF641IntAct24835590 details
TFAP2AACTN4IntAct24835590 details
TFAP2ADCAF7IntAct24835590 details
TFAP2AUNKLIntAct24835590 details
TFAP2ATPT1IntAct24835590 details
TFAP2ATIMM50IntAct24835590 details
TFAP2ATHY1IntAct24835590 details
TFAP2ASNTA1IntAct24835590 details
TFAP2ARCC1LIntAct24835590 details
TFAP2ARPL15IntAct24835590 details
TFAP2AERI3IntAct24835590 details
TFAP2APOTEFIntAct24835590 details
TFAP2ARHOAIntAct24835590 details
TFAP2APLA2G4BIntAct24835590 details
TFAP2AJMJD7-PLA2G4BIntAct24835590 details
TFAP2AKLF10IntAct24835590 details
TFAP2AGLULIntAct24835590 details
TFAP2ADNAJC19IntAct24835590 details
TFAP2ACTBP1IntAct24835590 details
TFAP2AATF7IPIntAct24835590 details
TFAP2AALDOAIntAct24835590 details
TFAP2AACY1IntAct24835590 details
TFAP2ADMRT3IntAct24835590 details
TFAP2AACTA2IntAct24835590 details
TFAP2APIAS1IntAct24835590 details
TFAP2APELI1IntAct24835590 details
TFAP2ANOMO3IntAct24835590 details
TFAP2ALGALS1IntAct24835590 details
TFAP2AIFI35IntAct24835590 details
TFAP2AHYIIntAct24835590 details
TFAP2AMOB2IntAct24835590 details
TFAP2AGNB2IntAct24835590 details
TFAP2AMKRN3BioGRID, IntAct25416956 details
TFAP2AGSTO2BioGRID, IntAct25416956 25910212 31515488 32296183 details
TFAP2AINCA1BioGRID, IntAct32296183 details
TFAP2ATP53BioGRID, HPRD12226108 16288208 details
TFAP2AAPCBioGRID, HPRD15331612 details
TFAP2ACITED4BioGRID, HPRD11744733 details
TFAP2AMYCBioGRID7729426 details
TFAP2AYBX1BioGRID, HPRD11973333 9830047 details
TFAP2APPARGBioGRID18310298 details
TFAP2AEPN1BioGRID15809337 16497222 details
TFAP2AKCTD1BioGRID19115315 details
TFAP2AEPS15BioGRID18524853 9490719 details
TFAP2ASRA1BioGRID20398657 details
TFAP2ARB1BioGRID, HPRD9632747 details
TFAP2ASP1BioGRID15705965 19074833 22182699 details
TFAP2AKCTD15BioGRID23382213 29665387 details
TFAP2APRKAA2BioGRID22561688 details
TFAP2ACSNK2BBioGRID21777522 details
TFAP2ACSNK2A1BioGRID21777522 details
TFAP2AXRCC6BioGRID19906305 details
TFAP2AXRCC5BioGRID19906305 details
TFAP2ARELABioGRID19074833 details
TFAP2ANFKB1BioGRID19074833 details
TFAP2APRKD1BioGRID18845787 details
TFAP2AVEGFABioGRID15342781 details
TFAP2ASH3BP4BioGRID, MINT16325581 details
TFAP2ACTNNB1BioGRID, HPRD15331612 details
TFAP2ADEKBioGRID, HPRD12595566 details
TFAP2AYY1BioGRID15870067 details
TFAP2ADNMT3ABioGRID19786833 details
TFAP2ABRCA1BioGRID21363924 details
TFAP2AAURKABioGRID21829699 details
TFAP2AEPAS1BioGRID23275444 details
TFAP2ADAB2BioGRID22323290 details
TFAP2AERBB4BioGRID20943952 details
TFAP2ATFAP2CBioGRID20459791 details
TFAP2ACFTRBioGRID20351096 details
TFAP2ATFAP2BBioGRID18843039 details
TFAP2AAP2B1BioGRID12900408 18843039 details
TFAP2AAP1M2BioGRID18843039 details
TFAP2ANR3C1BioGRID28611094 31182584 details
TFAP2AARBioGRID28611094 details
TFAP2AH3-3ABioGRID23828041 details
TFAP2AFCHO1BioGRID27237791 details
TFAP2AEGFRBioGRID8662849 details
TFAP2AADRB2BioGRID12163475 details
TFAP2AAP2M1BioGRID12900408 details
TFAP2AMEGF10BioGRID17643423 details
TFAP2ACASP1HPRD11438643 details
TFAP2ACASP3HPRD11438643 details
TFAP2ACASP6HPRD11438643 details
TFAP2AWWP1HPRD9169421 details
TFAP2AWWP2HPRD9169421 details
TFAP2AMAGI1HPRD9169421 details
TFAP2ALDLRAP1HPRD12221107 details
TFAP2AEPN2HPRD10567358 details
TFAP2ASYT1HPRD8087843 details
TFAP2AHIP1HPRD11604514 details
TFAP2ACLTCHPRD1587861 details
TFAP2ASUMO4HPRD16236267 details
TFAP2AGRB2IntAct12577067 details
TFAP2AAIM2BioGRID, IntAct25665578 details
TFAP2APYHIN1BioGRID, IntAct25665578 details
TFAP2AMAXBioGRID, MINT25609649 details
TFAP2AFOXB1BioGRID, MINT25609649 details
TFAP2AFOXE1BioGRID, MINT25609649 details
TFAP2AJUNBioGRID, MINT25609649 details
TFAP2AEEDBioGRID, IntAct26496610 details
TFAP2AAP4E1BioGRID, IntAct26496610 details
TFAP2AACOT1BioGRID, IntAct26186194 28514442 details
TFAP2ABAG3BioGRID23824909 details
TFAP2AHECW2BioGRID24163370 details
TFAP2ATFAP2DBioGRID26186194 details
TFAP2AEEFSECBioGRID26344197 details
TFAP2AEWSR1BioGRID24999758 details
TFAP2AHIRABioGRID23602572 details
TFAP2AUBN1BioGRID23602572 details
TFAP2AASF1ABioGRID23602572 details
TFAP2ASOX2BioGRID28794006 details
TFAP2AH4C1BioGRID30804502 details
TFAP2ABRD4BioGRID32416067 details
TFAP2ACOILBioGRID34079125 details
TFAP2AFOXA1IntAct24835590 details
TFAP2AESR1IntAct24835590 details
TFAP2AFREM2IntAct24835590 details
TFAP2ACCL27IntAct33179750 details
TFAP2ACCL4IntAct33179750 details
TFAP2ACCL28IntAct33179750 details
TFAP2ACCL4L2IntAct33179750 details
TFAP2ACCL5IntAct33179750 details
TFAP2ACX3CL1IntAct33179750 details
TFAP2ACSF2IntAct33179750 details
TFAP2ACXCL8IntAct33179750 details
TFAP2AIFNA16IntAct33179750 details
TFAP2AIFNL1IntAct33179750 details
TFAP2AIL12BIntAct33179750 details
TFAP2AIL17BIntAct33179750 details
TFAP2AIL22IntAct33179750 details
TFAP2AIL20IntAct33179750 details
TFAP2AIL3IntAct33179750 details
TFAP2AIL32IntAct33179750 details
TFAP2AKITLGIntAct33179750 details
TFAP2APPBPIntAct33179750 details
TFAP2ATNFIntAct33179750 details
TFAP2AXCL2IntAct33179750 details
TFAP2AELAVL1BioGRID19322201 details