Entity Details

Primary name USF1
Entity type gene
Source Source Link

Details

PrimaryID7391
RefseqGeneNG_011612
SymbolUSF1
Nameupstream transcription factor 1
Chromosome1
Location1q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-25
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsUSF1_HUMAN

GO terms

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GOName
GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose
GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001666 response to hypoxia
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006006 glucose metabolic process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009411 response to UV
GO:0019086 late viral transcription
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0032869 cellular response to insulin stimulus
GO:0042593 glucose homeostasis
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044877 protein-containing complex binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045990 carbon catabolite regulation of transcription
GO:0046982 protein heterodimerization activity
GO:0051918 negative regulation of fibrinolysis
GO:0055088 lipid homeostasis
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Disease IDSourceNameDescription
602491 OMIMHyperlipidemia, familial combined, 1 (FCHL1)A disorder characterized by a variable pattern of elevated levels of serum total cholesterol, triglycerides or both. It is observed in a percentage of individuals with premature coronary heart disease. Disease susceptibility is associated with variants affecting the gene represented in this entry.

Interactions

85 interactions

InteractorPartnerSourcesPublicationsLink
USF1USF2BioGRID, HPRD, IntAct15014447 16943425 17353931 17846119 18817855 19303849 21653943 26496610 28514442 8576131 9053857 details
USF1KAT2BBioGRID, IntAct19303849 details
USF1PLEKHF2BioGRID, MINT21516116 details
USF1FOSL1BioGRID, HPRD, IntAct25416956 32296183 9160889 details
USF1TRAF2BioGRID, IntAct25416956 details
USF1USF1BioGRID, HPRD, IntAct17846119 25416956 32296183 8306960 8576131 9160889 details
USF1MAP3K7CLBioGRID, IntAct32296183 details
USF1SNW1BioGRID, IntAct32296183 details
USF1LAP3BioGRID, IntAct32296183 details
USF1FGFR3IntAct32814053 details
USF1HRASIntAct32814053 details
USF1UBQLN1IntAct32814053 details
USF1GTF2IBioGRID, HPRD16943425 1961251 21653943 9384587 details
USF1TCFL5BioGRID12923186 details
USF1APPBioGRID21832049 details
USF1TCF3BioGRID9050988 details
USF1FOSBioGRID25416956 details
USF1PPARGC1ABioGRID12611894 details
USF1FBXO7BioGRID27503909 details
USF1TAOK2BioGRID30381292 details
USF1HOMEZBioGRID32296183 details
USF1EP300BioGRID17970752 details
USF1SMARCA4BioGRID16195385 details
USF1E2F3BioGRID15014447 details
USF1PRMT1BioGRID17846119 21653943 details
USF1SETD1ABioGRID17846119 21653943 details
USF1HCFC1BioGRID17846119 21653943 details
USF1ASH2LBioGRID17846119 21653943 details
USF1RBBP5BioGRID17846119 21653943 details
USF1WDR5BioGRID17846119 21653943 details
USF1CHD8BioGRID17846119 21653943 details
USF1BPTFBioGRID17846119 21653943 details
USF1SMARCA5BioGRID17846119 details
USF1SMARCA1BioGRID17846119 21653943 details
USF1RBBP7BioGRID17846119 details
USF1RBBP4BioGRID17846119 21653943 details
USF1TRRAPBioGRID17846119 21653943 details
USF1GTF3C1BioGRID17846119 21653943 details
USF1GTF2IRD1BioGRID17846119 details
USF1TAF6BioGRID17846119 21653943 details
USF1MAXBioGRID21653943 details
USF1NFYAHPRD12791656 details
USF1ESR1HPRD15111769 details
USF1PARP1BioGRID, IntAct19303849 details
USF1PRKDCBioGRID, HPRD, IntAct19303849 details
USF1XRCC6BioGRID, IntAct19303849 details
USF1TOP2BBioGRID, IntAct19303849 details
USF1XRCC5BioGRID, IntAct19303849 details
USF1HDAC9HPRD, IntAct19303849 details
USF1PPP1CCIntAct19303849 details
USF1SREBF1BioGRID, IntAct19303849 details
USF1ESCO2BioGRID, IntAct26496610 details
USF1COX2IntAct26496610 details
USF1PLXNA3BioGRID, IntAct26496610 details
USF1KIF21BBioGRID, IntAct26496610 details
USF1EME1BioGRID, IntAct26496610 details
USF1RCL1BioGRID, IntAct26496610 details
USF1TRMT13BioGRID, IntAct26496610 details
USF1ASS1BioGRID, IntAct26496610 details
USF1ATP5PDBioGRID, IntAct26496610 details
USF1PCF11BioGRID, IntAct26496610 details
USF1STT3ABioGRID, IntAct26496610 details
USF1AFG3L2BioGRID, IntAct26496610 details
USF1UBR4BioGRID, IntAct26496610 details
USF1DICER1BioGRID, IntAct26496610 details
USF1ZNF644BioGRID, IntAct26496610 details
USF1BATF3BioGRID, IntAct28514442 details
USF1TRIM11BioGRID, IntAct28514442 details
USF1ADAMTS12BioGRID, IntAct26186194 28514442 details
USF1FHL2BioGRID, IntAct28514442 details
USF1KLC1BioGRID, IntAct28514442 details
USF1H2AZ1BioGRID, IntAct30021884 details
USF1BAG3BioGRID23824909 details
USF1PSG1BioGRID26186194 details
USF1EWSR1BioGRID24999758 details
USF1MAP3K4BioGRID26496610 details
USF1MCATBioGRID26496610 details
USF1ESR2BioGRID29509190 details
USF1H4C1BioGRID30804502 details
USF1CICBioGRID29844126 details
USF1FASNIntAct19303849 details
USF1RORCIntAct22891280 details
USF1CCL18IntAct33179750 details
USF1XCL1IntAct33179750 details
USF1ELAVL1BioGRID19322201 details