Entity Details

Primary name ARHGEF7
Entity type gene
Source Source Link

Details

PrimaryID8874
RefseqGene
SymbolARHGEF7
NameRho guanine nucleotide exchange factor 7
Chromosome13
Location13q34
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-04-13
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsARHG7_HUMAN

GO terms

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GOName
GO:0001726 ruffle
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0007030 Golgi organization
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007399 nervous system development
GO:0010763 positive regulation of fibroblast migration
GO:0019901 protein kinase binding
GO:0030027 lamellipodium
GO:0030032 lamellipodium assembly
GO:0032991 protein-containing complex
GO:0035556 intracellular signal transduction
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0043005 neuron projection
GO:0043015 gamma-tubulin binding
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0048013 ephrin receptor signaling pathway
GO:0048041 focal adhesion assembly
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0097431 mitotic spindle pole
GO:0098794 postsynapse
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1904424 regulation of GTP binding
GO:1905833 negative regulation of microtubule nucleation
GO:2000394 positive regulation of lamellipodium morphogenesis

Diseases

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Interactions

80 interactions

InteractorPartnerSourcesPublicationsLink
ARHGEF7CBLBBioGRID, HPRD, MINT12935897 16228008 details
ARHGEF7SCRIBBioGRID, HPRD, IntAct, MINT15182672 15975580 19041750 19555689 21132015 24550280 26617989 details
ARHGEF7GIT1BioGRID, HPRD, IntAct, MINT10428811 10896954 12473661 15082779 16628223 16787945 17467235 21295525 25742295 28514442 32203420 details
ARHGEF7GIT2BioGRID, HPRD, IntAct, MINT10428811 10896954 15212761 16628223 28514442 32203420 details
ARHGEF7PAK1BioGRID, HPRD, IntAct, MINT10330411 11157752 16101281 16407834 16492808 16628223 20936779 23455922 26264872 28514442 29997244 31980649 32203420 32814053 details
ARHGEF7PAK2BioGRID, HPRD, IntAct, MINT12226077 16374509 16787945 26496610 32203420 details
ARHGEF7ADAM15BioGRID, HPRD, MINT16374509 details
ARHGEF7RAC1BioGRID, DIP, HPRD, MINT14557270 15306850 16492808 19961560 24792722 25150978 details
ARHGEF7CBLBioGRID, MINT12935897 14505571 16407834 22588125 23175185 details
ARHGEF7LRRK2BioGRID, IntAct21048939 25500533 details
ARHGEF7HSPB1BioGRID, IntAct25277244 details
ARHGEF7EGFRBioGRID, IntAct24658140 25402006 31980649 details
ARHGEF7MEOX2BioGRID, IntAct25416956 details
ARHGEF7SH2D1ADIP, HPRD, IntAct16983070 25416956 details
ARHGEF7ARHGEF6BioGRID, HPRD, IntAct12499396 15306850 28514442 32203420 details
ARHGEF7CDC42BioGRID, DIP, HPRD14505571 15649357 16983070 25150978 31478661 details
ARHGEF7SHANK2BioGRID, HPRD12626503 32661924 details
ARHGEF7SHANK1BioGRID, HPRD12626503 details
ARHGEF7TUBB3BioGRID, HPRD16169070 details
ARHGEF7PPM1EBioGRID11864573 details
ARHGEF7PPM1FBioGRID, HPRD11864573 details
ARHGEF7PAK3BioGRID, HPRD9726964 details
ARHGEF7CALM1BioGRID22588125 details
ARHGEF7ITCHBioGRID17652093 26613292 28235806 details
ARHGEF7ERBINBioGRID15123239 details
ARHGEF7ARHGEF7BioGRID15212761 details
ARHGEF7PRKCGBioGRID29167402 details
ARHGEF7NOX1BioGRID16329988 details
ARHGEF7PRRG4BioGRID23873930 details
ARHGEF7YWHAGHPRD, IntAct, MINT15324660 17353931 28514442 details
ARHGEF7CASKMINT15975580 details
ARHGEF7TUBB4AIntAct16169070 details
ARHGEF7CERS2IntAct20195357 details
ARHGEF7NAA10IntAct21295525 details
ARHGEF7NCKIPSDBioGRID, HPRD, IntAct14559906 28514442 details
ARHGEF7SRGAP1DIP25150978 details
ARHGEF7PPP2R1ADIP25150978 details
ARHGEF7NCK1BioGRID, HPRD, IntAct10330411 14559906 31980649 details
ARHGEF7PXNBioGRID, HPRD, IntAct10330411 31980649 34079125 details
ARHGEF7FXR1MINT21653829 details
ARHGEF7FXR2MINT21653829 details
ARHGEF7GRB2BioGRID21706016 details
ARHGEF7IGBP1BioGRID29555726 details
ARHGEF7SNX27BioGRID31541095 details
ARHGEF7LATS1BioGRID32661924 details
ARHGEF7TGFBR2HPRD15761153 details
ARHGEF7WASHPRD14559906 details
ARHGEF7SMAD3IntAct18729074 details
ARHGEF7MCM7IntAct23764002 details
ARHGEF7SKP1BioGRID, IntAct27705803 details
ARHGEF7SLC33A1BioGRID, IntAct26496610 details
ARHGEF7NCK2BioGRID, IntAct26186194 28514442 details
ARHGEF7POTEB3BioGRID, IntAct28514442 details
ARHGEF7ICAM1BioGRID, IntAct28514442 details
ARHGEF7INAVABioGRID, IntAct28514442 details
ARHGEF7FBXO28BioGRID, IntAct28514442 details
ARHGEF7EXOC1BioGRID, IntAct28514442 details
ARHGEF7SYNCBioGRID, IntAct28514442 details
ARHGEF7CAMK4BioGRID, IntAct28514442 details
ARHGEF7LPXNBioGRID, IntAct28514442 details
ARHGEF7YWHAHIntAct28514442 details
ARHGEF7CD244DIP, HPRD16983070 details
ARHGEF7MAPTUniProt26269332 details
ARHGEF7MED4BioGRID, MINT25281560 details
ARHGEF7SNRPFBioGRID, IntAct32203420 details
ARHGEF7PSMB6BioGRID, IntAct32203420 details
ARHGEF7ZBTB33BioGRID, IntAct32203420 details
ARHGEF7TIMM13BioGRID, IntAct32203420 details
ARHGEF7KDM2ABioGRID26344197 details
ARHGEF7NTRK1BioGRID25921289 details
ARHGEF7KLHL2BioGRID28514442 details
ARHGEF7EFTUD2BioGRID28515276 details
ARHGEF7PRKD2BioGRID30652415 details
ARHGEF7HDAC2BioGRID30737378 details
ARHGEF7ERLIN1BioGRID32203420 details
ARHGEF7MYL6BBioGRID32203420 details
ARHGEF7ZYXBioGRID32203420 details
ARHGEF7TRIOBioGRID32203420 details
ARHGEF7VIRMABioGRID29507755 details
ARHGEF7DDX58BioGRID32513696 details