Entity Details

Primary name CD3E
Entity type gene
Source Source Link

Details

PrimaryID916
RefseqGeneNG_007383
SymbolCD3E
NameCD3e molecule
Chromosome11
Location11q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-06-11
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCD3E_HUMAN

GO terms

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GOName
GO:0001772 immunological synapse
GO:0001954 positive regulation of cell-matrix adhesion
GO:0002250 adaptive immune response
GO:0002669 positive regulation of T cell anergy
GO:0004888 transmembrane signaling receptor activity
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0007166 cell surface receptor signaling pathway
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007172 signal complex assembly
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007584 response to nutrient
GO:0009897 external side of plasma membrane
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016358 dendrite development
GO:0017124 SH3 domain binding
GO:0019901 protein kinase binding
GO:0021549 cerebellum development
GO:0030159 signaling receptor complex adaptor activity
GO:0031295 T cell costimulation
GO:0032729 positive regulation of interferon-gamma production
GO:0032743 positive regulation of interleukin-2 production
GO:0032753 positive regulation of interleukin-4 production
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin
GO:0042101 T cell receptor complex
GO:0042102 positive regulation of T cell proliferation
GO:0042105 alpha-beta T cell receptor complex
GO:0042110 T cell activation
GO:0042608 T cell receptor binding
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043197 dendritic spine
GO:0044297 cell body
GO:0045059 positive thymic T cell selection
GO:0045060 negative thymic T cell selection
GO:0045879 negative regulation of smoothened signaling pathway
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0046982 protein heterodimerization activity
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050776 regulation of immune response
GO:0050850 positive regulation of calcium-mediated signaling
GO:0050852 T cell receptor signaling pathway
GO:0065003 protein-containing complex assembly
GO:0097190 apoptotic signaling pathway

Diseases

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Interactions

42 interactions

InteractorPartnerSourcesPublicationsLink
CD3ENCK1BioGRID, HPRD, MINT12110186 17617578 18955169 details
CD3ENCK2BioGRID, HPRD, IntAct, MINT12110186 17617578 32296183 details
CD3EEPS8L1BioGRID, MINT17617578 18644376 details
CD3EZAP70BioGRID, HPRD, MINT11855827 7761456 8366117 8647168 8906806 details
CD3ESYKBioGRID, HPRD, MINT7761456 9698567 details
CD3ECCR7MINT22922463 details
CD3EMUC15BioGRID, IntAct32296183 details
CD3EZFPL1BioGRID, IntAct32296183 details
CD3EPKMYT1BioGRID, IntAct32296183 details
CD3EBNIP3BioGRID, IntAct32296183 details
CD3ENCLBioGRID, HPRD11115514 details
CD3EPOLR1GBioGRID, HPRD10373416 details
CD3ETOP2BBioGRID, HPRD8626450 details
CD3ESNTA1BioGRID15123239 details
CD3ECSKBioGRID8621646 details
CD3EADAM33BioGRID32296183 details
CD3EUBASH3ABioGRID31659016 details
CD3EEPS8L3MINT17617578 details
CD3EEPS8L2MINT17617578 details
CD3EEPS8MINT17617578 details
CD3ELCKBioGRID, HPRD, MINT11855827 14523017 details
CD3ESHC1HPRD, MINT11855827 details
CD3ECD3GBioGRID, HPRD, InnateDB20890284 2138083 9582308 details
CD3ECD3DHPRD, InnateDB20890284 9485181 9582308 details
CD3ECD247BioGRID, IntAct14523017 25241761 details
CD3ENCR1IntAct9625766 details
CD3EPIK3R1BioGRID, HPRD11689561 11855827 19190244 9312149 details
CD3EJAK3BioGRID11349123 details
CD3ELATBioGRID14523017 details
CD3ECD38BioGRID14523017 details
CD3EPIK3R2BioGRID19190244 details
CD3EUNC119HPRD14757743 details
CD3ETRAT1HPRD9687533 details
CD3ECD79BHPRD7541024 details
CD3EPTPN22BioGRID, HPRD, IntAct16461343 details
CD3ELNPEPBioGRID, IntAct26186194 28514442 details
CD3ETM2D3BioGRID, IntAct26186194 28514442 details
CD3EFAM241BBioGRID, IntAct26186194 28514442 details
CD3EGHDCBioGRID, IntAct26186194 28514442 details
CD3EGP1BBBioGRID, IntAct26186194 28514442 details
CD3EHLA-ABioGRID, IntAct26186194 28514442 details
CD3EITPRIPL1BioGRID26186194 details