Entity Details

Primary name ACVR2A
Entity type gene
Source Source Link

Details

PrimaryID92
RefseqGene
SymbolACVR2A
Nameactivin A receptor type 2A
Chromosome2
Location2q22.3-q23.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAVR2A_HUMAN

GO terms

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GOName
GO:0001702 gastrulation with mouth forming second
GO:0001934 positive regulation of protein phosphorylation
GO:0004674 protein serine/threonine kinase activity
GO:0004675 transmembrane receptor protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006468 protein phosphorylation
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007283 spermatogenesis
GO:0007368 determination of left/right symmetry
GO:0007498 mesoderm development
GO:0009952 anterior/posterior pattern specification
GO:0009986 cell surface
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0015026 coreceptor activity
GO:0019838 growth factor binding
GO:0030165 PDZ domain binding
GO:0030501 positive regulation of bone mineralization
GO:0030509 BMP signaling pathway
GO:0030513 positive regulation of BMP signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0032924 activin receptor signaling pathway
GO:0032927 positive regulation of activin receptor signaling pathway
GO:0034673 inhibin-betaglycan-ActRII complex
GO:0034711 inhibin binding
GO:0042713 sperm ejaculation
GO:0043084 penile erection
GO:0043235 receptor complex
GO:0043621 protein self-association
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048179 activin receptor complex
GO:0048185 activin binding
GO:0048706 embryonic skeletal system development
GO:0050999 regulation of nitric-oxide synthase activity
GO:0060011 Sertoli cell proliferation
GO:0071363 cellular response to growth factor stimulus
GO:0071773 cellular response to BMP stimulus
GO:0098821 BMP receptor activity

Diseases

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Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
ACVR2ADAXXBioGRID, MINT11483955 details
ACVR2ABMP2BioGRID, DIP18070108 25938661 details
ACVR2ASYNJ2BPBioGRID, HPRD11882656 15451561 details
ACVR2AINHBABioGRID, HPRD10746731 11266516 8242742 8389764 9202237 details
ACVR2AINHBBBioGRID, HPRD11266516 28126904 9202237 details
ACVR2ABMP6BioGRID, HPRD10504300 18070108 details
ACVR2ABMP7BioGRID, HPRD12667445 18070108 9748228 details
ACVR2AMAGI2BioGRID, HPRD10681527 15451561 details
ACVR2AERBINBioGRID15123239 details
ACVR2AGDF2BioGRID17311849 22718755 details
ACVR2ABMP10BioGRID22718755 details
ACVR2APRSS50BioGRID28650473 details
ACVR2ATDGF1BioGRID28126904 details
ACVR2ANODALBioGRID28126904 details
ACVR2ABMP4BioGRID28126904 details
ACVR2ADYNLT4HPRD16982625 details
ACVR2AINHABioGRID10746731 details
ACVR2AGDF5BioGRID, HPRD8702914 details
ACVR2AENGBioGRID, HPRD23967299 9872992 details
ACVR2AACVR1BBioGRID11927552 8612709 9892009 details
ACVR2AIGSF1BioGRID, HPRD11266516 details
ACVR2APEG10BioGRID15611116 details
ACVR2AACVR1BioGRID8242742 details
ACVR2ARGMBBioGRID15671031 details
ACVR2ABMPR2BioGRID23967299 details
ACVR2ABMPR1ABioGRID15940369 details
ACVR2ATGFBR3HPRD10746731 details
ACVR2AINHBCHPRD12651901 details
ACVR2AGDF9HPRD12135884 details
ACVR2AACVRL1HPRD10187774 details
ACVR2ATNFRSF10ABioGRID, IntAct28514442 details
ACVR2ARUSF1BioGRID, IntAct28514442 details
ACVR2AHAVCR2BioGRID, IntAct28514442 details
ACVR2APTGER3BioGRID, IntAct26186194 28514442 details
ACVR2ALDLRAD4BioGRID, IntAct26186194 28514442 details
ACVR2AMRAP2BioGRID, IntAct28514442 details
ACVR2ARNF11BioGRID, IntAct28514442 details
ACVR2APCDHAC1BioGRID, IntAct28514442 details
ACVR2AHEPACAM2BioGRID, IntAct26186194 28514442 details
ACVR2ALRRIQ1BioGRID, IntAct28514442 details
ACVR2AGINM1BioGRID, IntAct26186194 28514442 details
ACVR2ADAAM2BioGRID, IntAct28514442 details
ACVR2ATLR2BioGRID, IntAct28514442 details
ACVR2ATGFBR2BioGRID26186194 details