Entity Details

Primary name SLIT2
Entity type gene
Source Source Link

Details

PrimaryID9353
RefseqGeneNG_047105
SymbolSLIT2
Nameslit guidance ligand 2
Chromosome4
Location4p15.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-04-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSLIT2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0001657 ureteric bud development
GO:0001933 negative regulation of protein phosphorylation
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0002689 negative regulation of leukocyte chemotaxis
GO:0003180 aortic valve morphogenesis
GO:0003184 pulmonary valve morphogenesis
GO:0005095 GTPase inhibitor activity
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007411 axon guidance
GO:0008045 motor neuron axon guidance
GO:0008201 heparin binding
GO:0009986 cell surface
GO:0010593 negative regulation of lamellipodium assembly
GO:0010596 negative regulation of endothelial cell migration
GO:0014912 negative regulation of smooth muscle cell migration
GO:0016020 membrane
GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0021972 corticospinal neuron axon guidance through spinal cord
GO:0030308 negative regulation of cell growth
GO:0030336 negative regulation of cell migration
GO:0030837 negative regulation of actin filament polymerization
GO:0031290 retinal ganglion cell axon guidance
GO:0032870 cellular response to hormone stimulus
GO:0035385 Roundabout signaling pathway
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043116 negative regulation of vascular permeability
GO:0043237 laminin-1 binding
GO:0043394 proteoglycan binding
GO:0048495 Roundabout binding
GO:0048754 branching morphogenesis of an epithelial tube
GO:0048846 axon extension involved in axon guidance
GO:0050772 positive regulation of axonogenesis
GO:0050919 negative chemotaxis
GO:0050929 induction of negative chemotaxis
GO:0051058 negative regulation of small GTPase mediated signal transduction
GO:0051414 response to cortisol
GO:0060412 ventricular septum morphogenesis
GO:0061364 apoptotic process involved in luteolysis
GO:0070062 extracellular exosome
GO:0070100 negative regulation of chemokine-mediated signaling pathway
GO:0071504 cellular response to heparin
GO:0071672 negative regulation of smooth muscle cell chemotaxis
GO:0071676 negative regulation of mononuclear cell migration
GO:0090024 negative regulation of neutrophil chemotaxis
GO:0090027 negative regulation of monocyte chemotaxis
GO:0090260 negative regulation of retinal ganglion cell axon guidance
GO:0090288 negative regulation of cellular response to growth factor stimulus

Diseases

Show/Hide Table

Interactions

36 interactions

InteractorPartnerSourcesPublicationsLink
SLIT2SLIT2HPRD, MINT10102268 19498462 details
SLIT2ROBO1DIP, HPRD10102268 17848514 details
SLIT2GPC1BioGRID, HPRD10364234 11375980 details
SLIT2UBCBioGRID23314748 details
SLIT2OGTBioGRID32994395 details
SLIT2ETS1IntAct20195357 details
SLIT2LUMBioGRID, IntAct27173435 unassigned1312 details
SLIT2EXOSC9BioGRID, IntAct27173435 unassigned1312 details
SLIT2EXOSC2BioGRID, IntAct27173435 unassigned1312 details
SLIT2EXOSC7BioGRID, IntAct27173435 unassigned1312 details
SLIT2LRRC47BioGRID, IntAct27173435 unassigned1312 details
SLIT2RSRC1BioGRID, IntAct27173435 unassigned1312 details
SLIT2EXOSC4BioGRID, IntAct27173435 unassigned1312 details
SLIT2HOXA1MINT21653829 details
SLIT2ROBO4BioGRID12941633 details
SLIT2ROBO2HPRD10102268 details
SLIT2MYCBioGRID, IntAct17314511 details
SLIT2HSCBBioGRID, IntAct28380382 details
SLIT2DEFA1BioGRID, IntAct28514442 details
SLIT2DEFA1BIntAct28514442 details
SLIT2PRG3BioGRID, IntAct28514442 details
SLIT2PRICKLE3BioGRID, IntAct28514442 details
SLIT2TP53BP1BioGRID, MINT24981860 details
SLIT2CCDC8BioGRID24711643 details
SLIT2ANKRD12BioGRID26186194 28514442 details
SLIT2PTCH1BioGRID26186194 details
SLIT2LMBR1LBioGRID31073040 details
SLIT2BRD7BioGRID30940648 details
SLIT2BRD2BioGRID31753913 details
SLIT2RNF208BioGRID31862882 details
SLIT2RPS21BioGRID24981860 details
SLIT2CSNK1EBioGRID24981860 details
SLIT2PIP4K2ABioGRID24981860 details
SLIT2SEC61BBioGRID34079125 details
SLIT2APEX1BioGRID28986522 details
SLIT2MKRN2BioGRID32460013 details