Entity Details

Primary name MRP7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5T3U5
EntryNameMRP7_HUMAN
FullNameATP-binding cassette sub-family C member 10
TaxID9606
Evidenceevidence at protein level
Length1492
SequenceStatuscomplete
DateCreated2006-10-17
DateModified2021-06-02

Ontological Relatives

GenesABCC10

GO terms

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GOName
GO:0005524 ATP binding
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0006691 leukotriene metabolic process
GO:0008559 ABC-type xenobiotic transporter activity
GO:0015431 ABC-type glutathione S-conjugate transporter activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0055085 transmembrane transport
GO:0071716 leukotriene transport
GO:0140359 ABC-type transporter activity

Subcellular Location

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Subcellular Location
Basolateral cell membrane
Cell membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00091 CyclosporineDrugbanksmall molecule
DB00203 SildenafilDrugbanksmall molecule
DB00300 Tenofovir disoproxilDrugbanksmall molecule
DB00441 GemcitabineDrugbanksmall molecule
DB00541 VincristineDrugbanksmall molecule
DB00563 MethotrexateDrugbanksmall molecule
DB00661 VerapamilDrugbanksmall molecule
DB00694 DaunorubicinDrugbanksmall molecule
DB00773 EtoposideDrugbanksmall molecule
DB00783 EstradiolDrugbanksmall molecule
DB00987 CytarabineDrugbanksmall molecule
DB00997 DoxorubicinDrugbanksmall molecule
DB01229 PaclitaxelDrugbanksmall molecule
DB01248 DocetaxelDrugbanksmall molecule
DB04348 Taurocholic acidDrugbanksmall molecule
DB13952 Estradiol acetateDrugbanksmall molecule
DB13953 Estradiol benzoateDrugbanksmall molecule
DB13954 Estradiol cypionateDrugbanksmall molecule
DB13955 Estradiol dienanthateDrugbanksmall molecule
DB13956 Estradiol valerateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MRP7_HUMANHNRPD_HUMANBioGRID15231747 details