Entity Details

Primary name ER6L2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5T890
EntryNameER6L2_HUMAN
FullNameDNA excision repair protein ERCC-6-like 2
TaxID9606
Evidenceevidence at protein level
Length1561
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesERCC6L2

GO terms

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GOName
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005815 microtubule organizing center
GO:0016787 hydrolase activity
GO:0019901 protein kinase binding
GO:0032991 protein-containing complex
GO:0034614 cellular response to reactive oxygen species
GO:0036297 interstrand cross-link repair
GO:0070615 nucleosome-dependent ATPase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR000330 SNF2, N-terminalDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved siteSiteConserved site
IPR002999 Tudor domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR029256 Helicase-associated putative binding domainDomainDomain
IPR038718 SNF2-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ER6L2_HUMANCYREN_HUMANBioGRID, IntAct25416956 32296183 details
ER6L2_HUMANT11L1_HUMANBioGRID, IntAct32296183 details
ER6L2_HUMANNEK6_HUMANBioGRID20873783 details