Entity Details

Primary name SIGIR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6IA17
EntryNameSIGIR_HUMAN
FullNameSingle Ig IL-1-related receptor
TaxID9606
Evidenceevidence at protein level
Length410
SequenceStatuscomplete
DateCreated2005-09-27
DateModified2021-06-02

Ontological Relatives

GenesSIGIRR

GO terms

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GOName
GO:0001960 negative regulation of cytokine-mediated signaling pathway
GO:0005886 plasma membrane
GO:0006953 acute-phase response
GO:0007165 signal transduction
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032682 negative regulation of chemokine production
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0071345 cellular response to cytokine stimulus

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000157 Toll/interleukin-1 receptor homology (TIR) domainDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015621 Interleukin-1 receptor familyFamilyFamily
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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