Entity Details

Primary name NADE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6IA69
EntryNameNADE_HUMAN
FullNameGlutamine-dependent NAD(+) synthetase
TaxID9606
Evidenceevidence at protein level
Length706
SequenceStatuscomplete
DateCreated2006-05-30
DateModified2021-06-02

Ontological Relatives

GenesNADSYN1

GO terms

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GOName
GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0004359 glutaminase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009435 NAD biosynthetic process
GO:0019674 NAD metabolic process
GO:0034627 'de novo' NAD biosynthetic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR003010 Carbon-nitrogen hydrolaseDomainDomain
IPR003694 NAD(+) synthetaseFamilyFamily
IPR014445 Glutamine-dependent NAD(+) synthetaseFamilyFamily
IPR014729 Rossmann-like alpha/beta/alpha sandwich foldFamilyHomologous superfamily
IPR022310 NAD/GMP synthaseDomainDomain
IPR036526 Carbon-nitrogen hydrolase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00130 L-GlutamineDrugbanksmall molecule
DB00142 Glutamic acidDrugbanksmall molecule