Entity Details

Primary name DEN1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6P3S1
EntryNameDEN1B_HUMAN
FullNameDENN domain-containing protein 1B
TaxID9606
Evidenceevidence at protein level
Length775
SequenceStatuscomplete
DateCreated2007-09-11
DateModified2021-06-02

Ontological Relatives

GenesDENND1B

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0006897 endocytosis
GO:0015031 protein transport
GO:0016607 nuclear speck
GO:0030136 clathrin-coated vesicle
GO:0031267 small GTPase binding
GO:0032456 endocytic recycling
GO:0043231 intracellular membrane-bounded organelle
GO:0043547 positive regulation of GTPase activity
GO:0050776 regulation of immune response
GO:0050852 T cell receptor signaling pathway
GO:1901981 phosphatidylinositol phosphate binding
GO:2000553 positive regulation of T-helper 2 cell cytokine production

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR001194 cDENN domainDomainDomain
IPR005112 dDENN domainDomainDomain
IPR005113 uDENN domainDomainDomain
IPR037516 Tripartite DENN domainDomainDomain
IPR040032 DENN domain-containing protein 1A/1B/1CFamilyFamily
IPR043153 DENN domain, C-terminal lobeFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DEN1B_HUMANLNX1_HUMANBioGRID, IntAct32296183 details