Entity Details

Primary name KSR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6VAB6
EntryNameKSR2_HUMAN
FullNameKinase suppressor of Ras 2
TaxID9606
Evidenceevidence at protein level
Length950
SequenceStatuscomplete
DateCreated2004-12-21
DateModified2021-06-02

Ontological Relatives

GenesKSR2

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007265 Ras protein signal transduction
GO:0019722 calcium-mediated signaling
GO:0046872 metal ion binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR025561 Kinase suppressor of RAS, SAM-like domainFamilyFamily

Diseases

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