Entity Details

Primary name CD109_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6YHK3
EntryNameCD109_HUMAN
FullNameCD109 antigen
TaxID9606
Evidenceevidence at protein level
Length1445
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesCD109

GO terms

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GOName
GO:0001933 negative regulation of protein phosphorylation
GO:0001942 hair follicle development
GO:0002576 platelet degranulation
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0010839 negative regulation of keratinocyte proliferation
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031092 platelet alpha granule membrane
GO:0031225 anchored component of membrane
GO:0045616 regulation of keratinocyte differentiation
GO:0050431 transforming growth factor beta binding
GO:0061045 negative regulation of wound healing
GO:0072675 osteoclast fusion

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001599 Alpha-2-macroglobulinDomainDomain
IPR002890 Macroglobulin domainDomainDomain
IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroidFamilyHomologous superfamily
IPR009048 Alpha-macroglobulin, receptor-bindingDomainDomain
IPR011625 Alpha-2-macroglobulin, bait region domainDomainDomain
IPR011626 Alpha-macroglobulin-like, TED domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR019742 Alpha-2-macroglobulin, conserved siteSiteConserved site
IPR036595 Alpha-macroglobulin, receptor-binding domain superfamilyFamilyHomologous superfamily
IPR041555 Macroglobulin domain MG3DomainDomain
IPR041813 Alpha-2-macroglobulin, TED domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CD109_HUMANEGFR_HUMANBioGRID25724945 details