Entity Details

Primary name FRMD7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6ZUT3
EntryNameFRMD7_HUMAN
FullNameFERM domain-containing protein 7
TaxID9606
Evidenceevidence at protein level
Length714
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesFRMD7

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0007399 nervous system development
GO:0010592 positive regulation of lamellipodium assembly
GO:0010975 regulation of neuron projection development
GO:0030426 growth cone
GO:0032091 negative regulation of protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0051497 negative regulation of stress fiber assembly

Subcellular Location

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Subcellular Location
Cell projection

Domains

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DomainNameCategoryType
IPR000299 FERM domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR014847 FERM adjacent (FA)DomainDomain
IPR018979 FERM, N-terminalDomainDomain
IPR018980 FERM, C-terminal PH-like domainDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR041788 FARP1/FARP2/FRMD7, FERM domain C-lobeDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
FRMD7_HUMANICLN_HUMANBioGRID, IntAct32296183 details
FRMD7_HUMANCSKP_HUMANBioGRID23406872 details