Entity Details

Primary name IFNL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IU54
EntryNameIFNL1_HUMAN
FullNameInterferon lambda-1
TaxID9606
Evidenceevidence at protein level
Length200
SequenceStatuscomplete
DateCreated2004-11-23
DateModified2021-06-02

Ontological Relatives

GenesIFNL1

GO terms

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GOName
GO:0002829 negative regulation of type 2 immune response
GO:0005102 signaling receptor binding
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0008285 negative regulation of cell population proliferation
GO:0019221 cytokine-mediated signaling pathway
GO:0032002 interleukin-28 receptor complex
GO:0032003 interleukin-28 receptor binding
GO:0032696 negative regulation of interleukin-13 production
GO:0032714 negative regulation of interleukin-5 production
GO:0032729 positive regulation of interferon-gamma production
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0043381 negative regulation of memory T cell differentiation
GO:0045087 innate immune response
GO:0045345 positive regulation of MHC class I biosynthetic process
GO:0045581 negative regulation of T cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0050778 positive regulation of immune response
GO:0051607 defense response to virus

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR029177 Interferon lambdaFamilyFamily
IPR038326 Interferon lambda superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
IFNL1_HUMANINLR1_HUMANHPRD, IntAct12469119 20934432 details