Entity Details

Primary name UNC5B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IZJ1
EntryNameUNC5B_HUMAN
FullNameNetrin receptor UNC5B
TaxID9606
Evidenceevidence at protein level
Length945
SequenceStatuscomplete
DateCreated2004-10-11
DateModified2021-06-02

Ontological Relatives

GenesUNC5B

GO terms

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GOName
GO:0001525 angiogenesis
GO:0005042 netrin receptor activity
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0007411 axon guidance
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016021 integral component of membrane
GO:0033564 anterior/posterior axon guidance
GO:0043524 negative regulation of neuron apoptotic process
GO:0045121 membrane raft
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

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Subcellular Location
Cell membrane
Membrane raft

Domains

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DomainNameCategoryType
IPR000488 Death domainDomainDomain
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR000906 ZU5 domainDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR033772 UPA domainDomainDomain
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR037936 Netrin receptor UNC5FamilyFamily
IPR042156 UNC5B, death domainDomainDomain

Diseases

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