Entity Details

Primary name LEG9_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00182
EntryNameLEG9_HUMAN
FullNameGalectin-9
TaxID9606
Evidenceevidence at protein level
Length355
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesLGALS9

GO terms

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GOName
GO:0002519 natural killer cell tolerance induction
GO:0005534 galactose binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007565 female pregnancy
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016936 galactoside binding
GO:0019899 enzyme binding
GO:0030246 carbohydrate binding
GO:0032496 response to lipopolysaccharide
GO:0032682 negative regulation of chemokine production
GO:0032689 negative regulation of interferon-gamma production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032729 positive regulation of interferon-gamma production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032733 positive regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032736 positive regulation of interleukin-13 production
GO:0032753 positive regulation of interleukin-4 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032834 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
GO:0038066 p38MAPK cascade
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043305 negative regulation of mast cell degranulation
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity
GO:0046007 negative regulation of activated T cell proliferation
GO:0046598 positive regulation of viral entry into host cell
GO:0048030 disaccharide binding
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060135 maternal process involved in female pregnancy
GO:0062023 collagen-containing extracellular matrix
GO:0070241 positive regulation of activated T cell autonomous cell death
GO:0070371 ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070555 response to interleukin-1
GO:0071346 cellular response to interferon-gamma
GO:0071636 positive regulation of transforming growth factor beta production
GO:0071639 positive regulation of monocyte chemotactic protein-1 production
GO:0098586 cellular response to virus
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2000510 positive regulation of dendritic cell chemotaxis
GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000670 positive regulation of dendritic cell apoptotic process
GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:2001200 positive regulation of dendritic cell differentiation
GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR001079 Galectin, carbohydrate recognition domainDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR044156 Galectin-likeFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB04472 (R)-1-Para-Nitro-Phenyl-2-Azido-EthanolDrugbanksmall molecule