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Entity Details
Primary name
ARG28_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q8N1W1
EntryName
ARG28_HUMAN
FullName
Rho guanine nucleotide exchange factor 28
TaxID
9606
Evidence
evidence at protein level
Length
1705
SequenceStatus
complete
DateCreated
2008-03-18
DateModified
2021-06-02
Ontological Relatives
Genes
ARHGEF28
GO terms
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GO
Name
GO:0000902
cell morphogenesis
GO:0003723
RNA binding
GO:0005085
guanyl-nucleotide exchange factor activity
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0030154
cell differentiation
GO:0035023
regulation of Rho protein signal transduction
GO:0035556
intracellular signal transduction
GO:0046872
metal ion binding
GO:0048013
ephrin receptor signaling pathway
Subcellular Location
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Subcellular Location
Cell membrane
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR000219
Dbl homology (DH) domain
Domain
Domain
IPR001849
Pleckstrin homology domain
Domain
Domain
IPR002219
Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain
Domain
IPR011993
PH-like domain superfamily
Family
Homologous superfamily
IPR035899
Dbl homology (DH) domain superfamily
Family
Homologous superfamily
IPR037819
ARHGEF28, PH domain
Domain
Domain
IPR041020
ARHGEF1-like, PH domain
Domain
Domain
Diseases
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Drugs
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Interactions
15 interactions
Interactor
Partner
Sources
Publications
Link
ARG28_HUMAN
CTG1B_HUMAN
BioGRID, IntAct
32296183
details
ARG28_HUMAN
CALR_HUMAN
IntAct
32814053
details
ARG28_HUMAN
ODO2_HUMAN
IntAct
32814053
details
ARG28_HUMAN
NEK7_HUMAN
IntAct
32814053
details
ARG28_HUMAN
RHOA_HUMAN
BioGRID, HPRD
32203420
9199174
details
ARG28_HUMAN
1433F_HUMAN
HPRD
11533041
details
ARG28_HUMAN
JIP1_HUMAN
HPRD
10574993
details
ARG28_HUMAN
ARHG9_HUMAN
BioGRID, IntAct
32203420
details
ARG28_HUMAN
ARHGI_HUMAN
BioGRID, IntAct
32203420
details
ARG28_HUMAN
GNA13_HUMAN
BioGRID
17595347
details
ARG28_HUMAN
GNA12_HUMAN
BioGRID
17595347
details
ARG28_HUMAN
TADBP_HUMAN
BioGRID
22941224
details
ARG28_HUMAN
FUS_HUMAN
BioGRID
22941224
details
ARG28_HUMAN
SQSTM_HUMAN
BioGRID
22941224
details
ARG28_HUMAN
1433E_HUMAN
HPRD
11533041
details
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