Entity Details

Primary name OGFD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N543
EntryNameOGFD1_HUMAN
FullNameProlyl 3-hydroxylase OGFOD1
TaxID9606
Evidenceevidence at protein level
Length542
SequenceStatuscomplete
DateCreated2007-05-29
DateModified2021-06-02

Ontological Relatives

GenesOGFOD1

GO terms

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GOName
GO:0005506 iron ion binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006449 regulation of translational termination
GO:0008283 cell population proliferation
GO:0010494 cytoplasmic stress granule
GO:0018126 protein hydroxylation
GO:0019511 peptidyl-proline hydroxylation
GO:0031418 L-ascorbic acid binding
GO:0031543 peptidyl-proline dioxygenase activity
GO:0031544 peptidyl-proline 3-dioxygenase activity
GO:0034063 stress granule assembly

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR005123 Oxoglutarate/iron-dependent dioxygenaseDomainDomain
IPR006620 Prolyl 4-hydroxylase, alpha subunitDomainDomain
IPR019601 Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domainDomainDomain
IPR039558 Prolyl 3,4-dihydroxylase TPA1/OFD1, N-terminal domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00126 Ascorbic acidDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
OGFD1_HUMANFEM1A_HUMANBioGRID, IntAct32296183 details
OGFD1_HUMANRS23_HUMANBioGRID, IntAct32296183 details
OGFD1_HUMANDNLI4_HUMANBioGRID22990118 details