Entity Details

Primary name NEK11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NG66
EntryNameNEK11_HUMAN
FullNameSerine/threonine-protein kinase Nek11
TaxID9606
Evidenceevidence at protein level
Length645
SequenceStatuscomplete
DateCreated2005-09-13
DateModified2021-06-02

Ontological Relatives

GenesNEK11

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006468 protein phosphorylation
GO:0007059 chromosome segregation
GO:0016572 histone phosphorylation
GO:0031573 mitotic intra-S DNA damage checkpoint signaling
GO:0035556 intracellular signal transduction
GO:0046872 metal ion binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901990 regulation of mitotic cell cycle phase transition

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB08912 DabrafenibDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule