Entity Details

Primary name FAAH1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00519
EntryNameFAAH1_HUMAN
FullNameFatty-acid amide hydrolase 1
TaxID9606
Evidenceevidence at protein level
Length579
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesFAAH

GO terms

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GOName
GO:0004040 amidase activity
GO:0005789 endoplasmic reticulum membrane
GO:0005856 cytoskeleton
GO:0009062 fatty acid catabolic process
GO:0016021 integral component of membrane
GO:0017064 fatty acid amide hydrolase activity
GO:0019369 arachidonic acid metabolic process
GO:0031090 organelle membrane
GO:0047372 acylglycerol lipase activity
GO:0052651 monoacylglycerol catabolic process
GO:0102077 oleamide hydrolase activity
GO:0103073 anandamide amidohydrolase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Endomembrane system

Domains

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DomainNameCategoryType
IPR020556 Amidase, conserved siteSiteConserved site
IPR023631 Amidase signature domainDomainDomain
IPR030560 Fatty-acid amide hydrolase 1FamilyFamily
IPR036928 Amidase signature (AS) superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00316 AcetaminophenDrugbanksmall molecule
DB00599 ThiopentalDrugbanksmall molecule
DB00818 PropofolDrugbanksmall molecule
DB02465 Methoxy arachidonyl fluorophosphonateDrugbanksmall molecule
DB06894 1-DodecanolDrugbanksmall molecule
DB08385 4-(quinolin-3-ylmethyl)piperidine-1-carboxylic acidDrugbanksmall molecule
DB08400 4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzyl)piperidine-1-carboxylic acidDrugbanksmall molecule
DB09061 CannabidiolDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule
DB14009 Medical CannabisDrugbankbiotech
DB14011 NabiximolsDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
FAAH1_HUMANNT2NA_HUMANBioGRID, IntAct25416956 details
FAAH1_HUMANNT2NC_HUMANBioGRID25416956 details
FAAH1_HUMANCXCR2_HUMANIntAct26617989 details