Entity Details

Primary name NFIB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00712
EntryNameNFIB_HUMAN
FullNameNuclear factor 1 B-type
TaxID9606
Evidenceevidence at protein level
Length420
SequenceStatuscomplete
DateCreated2001-06-01
DateModified2021-06-02

Ontological Relatives

GenesNFIB

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001650 fibrillar center
GO:0002062 chondrocyte differentiation
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006260 DNA replication
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007420 brain development
GO:0010001 glial cell differentiation
GO:0021740 principal sensory nucleus of trigeminal nerve development
GO:0021960 anterior commissure morphogenesis
GO:0043392 negative regulation of DNA binding
GO:0044300 cerebellar mossy fiber
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060486 club cell differentiation
GO:0060509 type I pneumocyte differentiation
GO:0060510 type II pneumocyte differentiation
GO:0061141 lung ciliated cell differentiation
GO:0071679 commissural neuron axon guidance
GO:0140416 transcription regulator inhibitor activity
GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000791 negative regulation of mesenchymal cell proliferation involved in lung development
GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000647 CTF transcription factor/nuclear factor 1FamilyFamily
IPR003619 MAD homology 1, Dwarfin-typeDomainDomain
IPR019548 CTF transcription factor/nuclear factor 1, N-terminalDomainDomain
IPR019739 CTF transcription factor/nuclear factor 1, conserved siteSiteConserved site
IPR020604 CTF transcription factor/nuclear factor 1, DNA-binding domainDomainDomain

Diseases

Show/Hide Table