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Entity Details
Primary name
MRTFA_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q969V6
EntryName
MRTFA_HUMAN
FullName
Myocardin-related transcription factor A
TaxID
9606
Evidence
evidence at protein level
Length
931
SequenceStatus
complete
DateCreated
2003-06-27
DateModified
2021-06-02
Ontological Relatives
Genes
MRTFA
GO terms
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GO
Name
GO:0003713
transcription coactivator activity
GO:0003779
actin binding
GO:0003785
actin monomer binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0010735
positive regulation of transcription via serum response element binding
GO:0030036
actin cytoskeleton organization
GO:0043522
leucine zipper domain binding
GO:0044319
wound healing, spreading of cells
GO:0045944
positive regulation of transcription by RNA polymerase II
GO:0051145
smooth muscle cell differentiation
Subcellular Location
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Subcellular Location
Cytoplasm
Nucleus
Domains
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Domain
Name
Category
Type
IPR003034
SAP domain
Domain
Domain
IPR004018
RPEL repeat
Repeat
Repeat
IPR029992
MKL/myocardin-like protein 1
Family
Family
IPR036361
SAP domain superfamily
Family
Homologous superfamily
IPR043451
Myocardin-like
Family
Family
Diseases
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Drugs
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Drug
Name
Source
Type
DB08080
Latrunculin B
Drugbank
small molecule
Interactions
19 interactions
Interactor
Partner
Sources
Publications
Link
MRTFA_HUMAN
SRF_HUMAN
BioGRID, HPRD, IntAct
12397177
14565952
15610731
17599918
21965288
details
MRTFA_HUMAN
IMA4_HUMAN
MINT
20818336
details
MRTFA_HUMAN
MYCD_HUMAN
BioGRID, HPRD
14970199
details
MRTFA_HUMAN
KDM3A_HUMAN
BioGRID
17991879
details
MRTFA_HUMAN
SMCA4_HUMAN
BioGRID
17599918
details
MRTFA_HUMAN
MVP_HUMAN
BioGRID
24722188
details
MRTFA_HUMAN
NCOA3_HUMAN
BioGRID
17360478
details
MRTFA_HUMAN
TRI54_HUMAN
BioGRID
31391242
details
MRTFA_HUMAN
UBC9_HUMAN
HPRD
16098147
details
MRTFA_HUMAN
MRTFB_HUMAN
BioGRID, HPRD, IntAct
14565952
details
MRTFA_HUMAN
SP16H_HUMAN
BioGRID
18036521
details
MRTFA_HUMAN
SSRP1_HUMAN
BioGRID
18036521
details
MRTFA_HUMAN
GSK3B_HUMAN
BioGRID
21965288
details
MRTFA_HUMAN
SMAD3_HUMAN
BioGRID
21965288
details
MRTFA_HUMAN
ACTB_HUMAN
BioGRID
21670154
34079125
details
MRTFA_HUMAN
DNMT1_HUMAN
BioGRID
25854163
details
MRTFA_HUMAN
EP300_HUMAN
BioGRID
26476216
details
MRTFA_HUMAN
MRTFA_HUMAN
HPRD
14565952
details
MRTFA_HUMAN
SUMO1_HUMAN
HPRD
16098147
details
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